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CATH Superfamily 2.102.10.10

Rieske [2Fe-2S] iron-sulphur domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Rieske [2Fe-2S] iron-sulphur domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3410: Biphenyl/naphthalene dioxygenase alpha subunit

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Benzene 1,2-dioxygenase. [EC: 1.14.12.3]
Benzene + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).
  • A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase and ferredoxin.
 11 A0A0A8J2Y4 A5HFU4 A5W4F2 I7B4T5 P0C618 Q07944 Q3LWS6 Q588I9 Q8VQU6 V9UYT7
(1 more...)
Toluene dioxygenase. [EC: 1.14.12.11]
Toluene + NADH + O(2) = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).
  • A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase, and a ferredoxin.
  • Some other aromatic compounds, including ethylbenzene, 4-xylene and some halogenated toluenes, are converted into the corresponding cis- dihydrodiols.
 5 A5W4F2 I7B4T5 P0C618 Q3LWS6 V9UYT7
Biphenyl 2,3-dioxygenase. [EC: 1.14.12.18]
Biphenyl + NADH + O(2) = (1S,2R)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+).
  • The enzyme from Burkholderia fungorum strain LB400 (previously Pseudomonas sp.) is part of a multicomponent system composed of an NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske- type iron-sulfur cluster and a catalytic mononuclear nonheme iron center.
  • Chlorine-substituted biphenyls can also act as substrates.
  • Similar to the three-component enzyme systems EC 1.14.12.3 and EC 1.14.12.11.
 4 A0A0X8R4R9 A0A100JT76 Q53122 S5GAZ4
3-phenylpropanoate dioxygenase. [EC: 1.14.12.19]
(1) 3-phenylpropanoate + NADH + O(2) = 3-(cis-5,6-dihydroxycyclohexa-1,3- dien-1-yl)propanoate + NAD(+). (2) (2E)-3-phenylprop-2-enoate + NADH + O(2) = (2E)-3-(2,3- dihydroxyphenyl)prop-2-enoate + NAD(+).
  • This enzyme catalyzes a step in the pathway of phenylpropanoid compounds degradation.
  • It catalyzes the insertion of both atoms of molecular oxygen into positions 2 and 3 of the phenyl ring of 3-phenylpropanoate or (2E)-3- phenylprop-2-enoate.
 4 A0A0G3H3H3 A0A0L0K6X1 A0A0X8R4R9 A1TDE1
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