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CATH Superfamily 2.102.10.10

Rieske [2Fe-2S] iron-sulphur domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Rieske [2Fe-2S] iron-sulphur domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1443: Putative 2Fe-2S cluster-containing dioxygenase sub...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Choline monooxygenase. [EC: 1.14.15.7]
Choline + O(2) + 2 reduced ferredoxin + 2 H(+) = betaine aldehyde hydrate + H(2)O + 2 oxidized ferredoxin.
  • Catalyzes the first step of glycine betaine synthesis.
  • In many bacteria, plants and animals, the osmoprotectant betaine is synthesized in two steps: (1) choline to betaine aldehyde and (2) betaine aldehyde to betaine.
  • Different enzymes are involved in the first reaction.
  • In plants, the reaction is catalyzed by this enzyme whereas in animals and many bacteria, it is catalyzed by either membrane-bound EC 1.1.99.1 or soluble EC 1.1.3.17.
  • The enzyme involved in the second step, EC 1.2.1.8, appears to be the same in plants, animals and bacteria.
  • In some bacteria, betaine is synthesized from glycine through the actions of EC 2.1.1.156 and EC 2.1.1.157.
  • Formerly EC 1.14.14.4.
 105 A0A023YY76 A0A025CQW6 A0A026V537 A0A027TSF9 A0A069XM75 A0A070CRV8 A0A070D196 A0A070SWA0 A0A073FWU7 A0A073HHC2
(95 more...)
Anthranilate 1,2-dioxygenase (deaminating, decarboxylating). [EC: 1.14.12.1]
Anthranilate + NAD(P)H + O(2) = catechol + CO(2) + NAD(P)(+) + NH(3).
    		 104 A0A026V537 A0A027TSF9 A0A069XM75 A0A070CRV8 A0A070D196 A0A070SWA0 A0A073FWU7 A0A073HHC2 A0A073URF4 A0A0A0FHR9
    (94 more...)
    Phthalate 4,5-dioxygenase. [EC: 1.14.12.7]
    Phthalate + NADH + O(2) = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2- dicarboxylate + NAD(+).
    • A system, containing a reductase which is an iron-sulfur flavoprotein (FMN), an iron-sulfur oxygenase, and no independent ferredoxin.
    		 3 A0A090NLN5 E2XGN2 Q32FS9
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