The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 45073: Epidermal growth factor-like protein 7

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Notch binding GO:0005112
Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
1 Q9QXT5 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q9QXT5 (/NAS)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
2 Q6AZ60 (/ISS) Q9UHF1 (/ISS)
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
2 Q6AZ60 (/ISS) Q9UHF1 (/ISS)
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
1 Q9QXT5 (/IEP)
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
1 Q9QXT5 (/IEP)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
1 Q9UHF1 (/IMP)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
1 Q9QXT5 (/ISO)
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
1 Q9QXT5 (/TAS)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 Q9QXT5 (/IDA)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q9UHF1 (/IMP)
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
1 Q9QXT5 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 Q6AZ60 (/ISS) Q9UHF1 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q9QXT5 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9QXT5 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support for cells or tissues.
1 Q9UHF1 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support for cells or tissues.
1 Q9QXT5 (/ISO)