The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 24553: Neurexin 2, isoform CRA_a

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
6 E9PUM9 (/IGI) E9PUN0 (/IGI) E9Q5N7 (/IGI) E9Q7X7 (/IGI) F6Y027 (/IGI) Q3UGZ9 (/IGI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 E9PUM9 (/IPI) E9PUN0 (/IPI) E9Q5N7 (/IPI) E9Q7X7 (/IPI) F6Y027 (/IPI) Q3UGZ9 (/IPI)
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Neuroligin family protein binding GO:0097109
Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
1 Q3UGZ9 (/IDA)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
1 Q3UGZ9 (/IPI)
Neuroligin family protein binding GO:0097109
Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
1 Q3UGZ9 (/IPI)

There are 25 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
6 E9PUM9 (/IGI) E9PUN0 (/IGI) E9Q5N7 (/IGI) E9Q7X7 (/IGI) F6Y027 (/IGI) Q3UGZ9 (/IGI)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
6 E9PUM9 (/IGI) E9PUN0 (/IGI) E9Q5N7 (/IGI) E9Q7X7 (/IGI) F6Y027 (/IGI) Q3UGZ9 (/IGI)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
6 E9PUM9 (/IGI) E9PUN0 (/IGI) E9Q5N7 (/IGI) E9Q7X7 (/IGI) F6Y027 (/IGI) Q3UGZ9 (/IGI)
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
6 E9PUM9 (/ISO) E9PUN0 (/ISO) E9Q5N7 (/ISO) E9Q7X7 (/ISO) F6Y027 (/ISO) Q3UGZ9 (/ISO)
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
6 E9PUM9 (/ISO) E9PUN0 (/ISO) E9Q5N7 (/ISO) E9Q7X7 (/ISO) F6Y027 (/ISO) Q3UGZ9 (/ISO)
Vocal learning GO:0042297
A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.
6 E9PUM9 (/ISO) E9PUN0 (/ISO) E9Q5N7 (/ISO) E9Q7X7 (/ISO) F6Y027 (/ISO) Q3UGZ9 (/ISO)
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
6 E9PUM9 (/ISO) E9PUN0 (/ISO) E9Q5N7 (/ISO) E9Q7X7 (/ISO) F6Y027 (/ISO) Q3UGZ9 (/ISO)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Gephyrin clustering involved in postsynaptic density assembly GO:0097116
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Neuroligin clustering involved in postsynaptic membrane assembly GO:0097118
The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
2 Q63374 (/ISS) Q9P2S2 (/ISS)
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
1 Q9P2S2 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q3UGZ9 (/IDA)
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
1 Q9P2S2 (/IMP)
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
1 Q9P2S2 (/IMP)
Vocal learning GO:0042297
A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.
1 Q9P2S2 (/IMP)
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
1 Q9P2S2 (/IMP)
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
1 Q3UGZ9 (/IDA)
Gephyrin clustering involved in postsynaptic density assembly GO:0097116
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
1 Q3UGZ9 (/IDA)
Neuroligin clustering involved in postsynaptic membrane assembly GO:0097118
The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
1 Q3UGZ9 (/IDA)
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
1 Q3UGZ9 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
6 E9PUM9 (/ISA) E9PUN0 (/ISA) E9Q5N7 (/ISA) E9Q7X7 (/ISA) F6Y027 (/ISA) Q3UGZ9 (/ISA)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
6 E9PUM9 (/IPI) E9PUN0 (/IPI) E9Q5N7 (/IPI) E9Q7X7 (/IPI) F6Y027 (/IPI) Q3UGZ9 (/IPI)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9P2S2 (/TAS)