The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 22070: Neurexin-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q63372 (/IPI) Q9CS84 (/IPI) Q9ULB1 (/IPI)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
2 Q9CS84 (/ISS) Q9ULB1 (/ISS)
Acetylcholine receptor binding GO:0033130
Interacting selectively and non-covalently with an acetylcholine receptor.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Neuroligin family protein binding GO:0097109
Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
2 Q28146 (/IPI) Q9CS84 (/IPI)
Neuroligin family protein binding GO:0097109
Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Receptor activity GO:0004872
Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
1 Q9ULB1 (/TAS)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
1 Q9CS84 (/IGI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q63372 (/IDA)
Acetylcholine receptor binding GO:0033130
Interacting selectively and non-covalently with an acetylcholine receptor.
1 Q9CS84 (/IDA)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
1 Q9CS84 (/IPI)

There are 50 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
2 Q9CS84 (/IMP) Q9ULB1 (/IMP)
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
2 Q9CS84 (/IMP) Q9ULB1 (/IMP)
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Positive regulation of synapse maturation GO:0090129
Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Gephyrin clustering involved in postsynaptic density assembly GO:0097116
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Neuroligin clustering involved in postsynaptic membrane assembly GO:0097118
The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial cells.
1 A1XQX0 (/IGI)
Sprouting angiogenesis GO:0002040
The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial cells.
1 A1XQX0 (/IMP)
Vesicle docking involved in exocytosis GO:0006904
The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
1 Q63372 (/IMP)
Vesicle docking involved in exocytosis GO:0006904
The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
1 Q9CS84 (/ISO)
Neuron cell-cell adhesion GO:0007158
The attachment of a neuron to another cell via adhesion molecules.
1 Q9ULB1 (/TAS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 Q9CS84 (/IGI)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
1 Q9CS84 (/IGI)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
1 Q9CS84 (/TAS)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
1 Q9ULB1 (/TAS)
Synapse assembly GO:0007416
The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
1 Q9CS84 (/IGI)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
1 Q9CS84 (/ISO)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
1 Q63372 (/ISS)
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
1 Q63372 (/TAS)
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
1 Q9CS84 (/ISO)
Adult behavior GO:0030534
Behavior in a fully developed and mature organism.
1 Q63372 (/ISS)
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
1 Q9ULB1 (/IMP)
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
1 Q9CS84 (/ISO)
Vocal learning GO:0042297
A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.
1 Q9ULB1 (/IMP)
Vocal learning GO:0042297
A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.
1 Q9CS84 (/ISO)
Neuromuscular process controlling balance GO:0050885
Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
1 Q9CS84 (/IMP)
Protein heterotetramerization GO:0051290
The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
1 Q63372 (/IDA)
Positive regulation of synapse assembly GO:0051965
Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
1 Q9CS84 (/IGI)
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
1 Q9CS84 (/IMP)
Prepulse inhibition GO:0060134
The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.
1 Q9CS84 (/IMP)
Prepulse inhibition GO:0060134
The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.
1 Q63372 (/ISS)
Regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178
Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 Q9CS84 (/IMP)
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
1 Q9ULB1 (/IMP)
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
1 Q9CS84 (/ISO)
Positive regulation of synapse maturation GO:0090129
Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
1 Q9CS84 (/IDA)
Postsynaptic membrane assembly GO:0097104
The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
1 Q9CS84 (/IDA)
Gephyrin clustering involved in postsynaptic density assembly GO:0097116
The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
1 Q9CS84 (/IDA)
Neuroligin clustering involved in postsynaptic membrane assembly GO:0097118
The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
1 Q9CS84 (/IDA)
Postsynaptic density protein 95 clustering GO:0097119
The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
1 Q9CS84 (/IDA)
Positive regulation of excitatory postsynaptic potential GO:2000463
Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
1 Q9CS84 (/IMP)
Regulation of grooming behavior GO:2000821
Any process that modulates the frequency, rate or extent of grooming behavior.
1 Q9CS84 (/IMP)
Regulation of grooming behavior GO:2000821
Any process that modulates the frequency, rate or extent of grooming behavior.
1 Q63372 (/ISS)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9CS84 (/IC) Q9ULB1 (/IC)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9CS84 (/ISS) Q9ULB1 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q63372 (/TAS) Q9ULB1 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 Q9CS84 (/IDA) Q9ULB1 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 Q63372 (/ISS) Q9ULB1 (/ISS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q9CS84 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q63372 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9CS84 (/ISO)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9ULB1 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q9CS84 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q63372 (/ISS)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 Q9CS84 (/IDA)
Vesicle GO:0031982
Any small, fluid-filled, spherical organelle enclosed by membrane.
1 Q9CS84 (/IDA)
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
1 Q9CS84 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q9CS84 (/IDA)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q9CS84 (/IPI)