The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Cysteine Rich Protein
".
FunFam 6128: Cysteine-rich protein 2 variant
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
32 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(22 more) |
AT DNA binding GO:0003680
Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Peptide binding GO:0042277
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q19641 (/IPI) Q9DCT8 (/IPI) Q9DCT8 (/IPI) Q9VCQ7 (/IPI) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
3 | P52943 (/TAS) P52943 (/TAS) P63255 (/TAS) |
AT DNA binding GO:0003680
Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
|
1 | P50238 (/IDA) |
AT DNA binding GO:0003680
Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
|
1 | P63254 (/ISO) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | P50238 (/IDA) |
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
|
1 | P63254 (/ISO) |
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
1 | P50238 (/IDA) |
DNA binding, bending GO:0008301
The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
1 | P63254 (/ISO) |
Peptide binding GO:0042277
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
|
1 | P50238 (/IDA) |
Peptide binding GO:0042277
Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
|
1 | P63254 (/ISO) |
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | Q9BIW5 (/IDA) |
There are 35 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Cellular response to antibiotic GO:0071236
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
2 | F1QZB0 (/IMP) F1QZB0 (/IMP) |
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | Q9DCT8 (/IDA) Q9DCT8 (/IDA) |
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
2 | Q9DCT8 (/IDA) Q9DCT8 (/IDA) |
Morphogenesis of a polarized epithelium GO:0001738
The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
|
1 | Q19641 (/IMP) |
Epithelial cell development GO:0002064
The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
|
1 | Q19641 (/IMP) |
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
|
1 | P50238 (/IEP) |
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
1 | Q9BIW5 (/IDA) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | P50238 (/TAS) |
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | P50238 (/TAS) |
Intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
|
1 | P50238 (/IDA) |
Intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
|
1 | P63254 (/ISO) |
Negative regulation of signal transduction GO:0009968
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
|
1 | Q9VCQ7 (/IMP) |
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
1 | P50238 (/IEP) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
1 | P50238 (/IDA) |
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
|
1 | P63254 (/ISO) |
Body morphogenesis GO:0010171
The process in which the anatomical structures of the soma are generated and organized.
|
1 | Q19641 (/IMP) |
Response to gamma radiation GO:0010332
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
|
1 | Q9VCQ7 (/IMP) |
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P50238 (/IEP) |
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
|
1 | Q17522 (/IMP) |
Digestive system process GO:0022600
A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
|
1 | Q17522 (/IMP) |
Cortical actin cytoskeleton organization GO:0030866
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
|
1 | Q9BIW5 (/TAS) |
Regulation of tube size GO:0035150
Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.
|
1 | Q19641 (/IMP) |
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
|
1 | Q9VCQ7 (/IMP) |
T cell proliferation GO:0042098
The expansion of a T cell population by cell division. Follows T cell activation.
|
1 | Q6Q6R3 (/IMP) |
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | Q17522 (/IEP) |
Nematode male tail tip morphogenesis GO:0045138
The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
|
1 | Q19641 (/IMP) |
Prostate gland stromal morphogenesis GO:0060741
The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.
|
1 | P50238 (/IEP) |
Cellular response to antibiotic GO:0071236
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
|
1 | P50238 (/IDA) |
Cellular response to antibiotic GO:0071236
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
|
1 | P63254 (/ISO) |
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
|
1 | P50238 (/IDA) |
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
|
1 | P63254 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
30 |
A0A1D8BBG5 (/ISS)
A4QNF7 (/ISS)
B5X5E7 (/ISS)
B9EPY4 (/ISS)
C1BGH2 (/ISS)
C1BW08 (/ISS)
C3KI09 (/ISS)
E2RE67 (/ISS)
E3TCV8 (/ISS)
E3TF98 (/ISS)
(20 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | P50238 (/IDA) Q19641 (/IDA) Q6Q6R3 (/IDA) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
3 | Q9BIW5 (/IDA) Q9DCT8 (/IDA) Q9DCT8 (/IDA) |
Phagocytic cup GO:0001891
An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.
|
1 | Q9BIW5 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P63254 (/ISO) |
Pseudopodium GO:0031143
A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.
|
1 | Q9BIW5 (/IDA) |
Macropinosome GO:0044354
A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.
|
1 | Q9BIW5 (/IDA) |
Exocytic vesicle GO:0070382
A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.
|
1 | Q9BIW5 (/IDA) |