The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cysteine Rich Protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1111: Zyxin, isoform H

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 H9XVP5 (/IPI) Q8I0G8 (/IPI) Q8T0F5 (/IPI) Q9N675 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
4 H9XVP5 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS)
Terminal branching, open tracheal system GO:0007430
Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Chitin-based cuticle sclerotization GO:0007593
The process of hardening of a chitin-based cuticle.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Liquid clearance, open tracheal system GO:0035002
The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Positive regulation of imaginal disc growth GO:0045572
Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Positive regulation of eclosion GO:0045805
Any process that activates or increases the frequency, rate or extent of eclosion.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Positive regulation of organ growth GO:0046622
Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)
Imaginal disc-derived wing expansion GO:0048526
The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.
4 H9XVP5 (/IMP) Q8I0G8 (/IMP) Q8T0F5 (/IMP) Q9N675 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
4 H9XVP5 (/IDA) Q8I0G8 (/IDA) Q8T0F5 (/IDA) Q9N675 (/IDA)
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
4 H9XVP5 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
4 H9XVP5 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
4 H9XVP5 (/ISS) Q8I0G8 (/ISS) Q8T0F5 (/ISS) Q9N675 (/ISS)
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
4 H9XVP5 (/IDA) Q8I0G8 (/IDA) Q8T0F5 (/IDA) Q9N675 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...