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CATH Superfamily 1.50.10.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2907: Squalene/oxidosqualene cyclases subfamily

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sporulenol synthase. [EC: 4.2.1.137]
Sporulenol = tetraprenyl-beta-curcumene + H(2)O.
  • The reaction occurs in the reverse direction.
  • Isolated from Bacillus subtilis.
  • Similar sesquarterpenoids are present in a number of Bacillus species.
 8 A0A0K6KHE6 A0A0K6KTG9 A0A0K6LYP0 A0A0K6MDT0 A0A164XYQ2 A0A1B2B4D4 L8AME5 Q796C3
Squalene--hopene cyclase. [EC: 5.4.99.17]
Squalene = hop-22(29)-ene.
  • The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129).
  • Hopene and hopanol are formed at a constant ratio of 5:1.
 3 A0A0M0L3Y6 A0A1G4LKA4 G4NQ27
Squalene--hopanol cyclase. [EC: 4.2.1.129]
Hopan-22-ol = squalene + H(2)O.
  • The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1.
 1 A0A0T8Q208
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