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CATH Superfamily 1.50.10.130

Terpene synthase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Terpene synthase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 896: Putative terpenoid synthase 5

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(Z)-gamma-bisabolene synthase. [EC: 4.2.3.40]
(2E,6E)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.
  • This sesquiterpenoid enzyme is constitutively expressed in the root, hydathodes and stigma of the plant Arabidopsis thaliana.
  • If the leaves of the plant are wounded, e.g. by cutting, the enzyme is also induced close to the wound site.
  • The sesquiterpenoids (E)-nerolidol and alpha-bisabolol are also produced by this enzyme as minor products.
 2 Q9T0J9 Q9T0K1
(+)-alpha-barbatene synthase. [EC: 4.2.3.69]
(2E,6E)-farnesyl diphosphate = (+)-alpha-barbatene + diphosphate.
  • The recombinant enzyme from the plant Arabidopsis thaliana produces 27.3% alpha-barbatene, 17.8% thujopsene (cf. EC 4.2.3.79) and 9.9% beta-chamigrene (cf. 4.2.3.78) plus traces of other sesquiterpenoids.
 1 Q4KSH9
Beta-chamigrene synthase. [EC: 4.2.3.78]
(2E,6E)-farnesyl diphosphate = (+)-beta-chamigrene + diphosphate.
  • The recombinant enzyme from the plant Arabidopsis thaliana produces 27.3% (+)-alpha-barbatene, 17.8% (+)-thujopsene and 9.9% (+)-beta- chamigrene plus traces of other sesquiterpenoids.
  • See EC 4.2.3.69 and EC 4.2.3.79.
 1 Q4KSH9
Thujopsene synthase. [EC: 4.2.3.79]
(2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate.
  • The recombinant enzyme from the plant Arabidopsis thaliana produces 27.3% (+)-alpha-barbatene, 17.8% (+)-thujopsene and 9.9% (+)-beta- chamigrene plus traces of other sesquiterpenoids.
  • See EC 4.2.3.69 and EC 4.2.3.78.
 1 Q4KSH9