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CATH Superfamily 1.50.10.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 18716: Glycosyl hydrolase, family 65

There are 10 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Maltose phosphorylase. [EC: 2.4.1.8]
Maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
    		 804 A0A011QTJ0 A0A011QTJ0 A0A011RNM3 A0A011RNM3 A0A011SHA1 A0A011SHA1 A0A023YWG9 A0A023YWG9 A0A025CZY5 A0A025CZY5
    (794 more...)
    Kojibiose phosphorylase. [EC: 2.4.1.230]
    2-alpha-D-glucosyl-D-glucose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
    • The enzyme from Thermoanaerobacter brockii can act with alpha-1,2- oligoglucans, such as selaginose, as substrate, but more slowly.
    • The enzyme is inactive when dissaccharides with linkages other than alpha-1,2 linkages, such as sophorose, trehalose, neotrehalose, nigerose, laminaribiose, maltose, cellobiose, isomaltose, gentiobiose, sucrose and lactose, are used as substrates.
    		 746 A0A024L419 A0A024L419 A0A026UZI1 A0A026UZI1 A0A028AC01 A0A028AC01 A0A028E550 A0A028E550 A0A045JAN7 A0A045JAN7
    (736 more...)
    Alpha,alpha-trehalose phosphorylase. [EC: 2.4.1.64]
    Alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
      		 442 A0A011QTJ0 A0A011QTJ0 A0A011RNM3 A0A011RNM3 A0A011SHA1 A0A011SHA1 A0A023YWG9 A0A023YWG9 A0A025CZY5 A0A025CZY5
      (432 more...)
      Trehalose 6-phosphate phosphorylase. [EC: 2.4.1.216]
      Alpha,alpha-trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.
      • The enzyme from Lactococcus lactis is specific for trehalose 6-phosphate.
      • Differs from EC 2.4.1.64 in that trehalose is not a substrate.
      		 158 A0A059MGK3 A0A059MGK3 A0A062XDN3 A0A062XDN3 A0A087FAZ1 A0A087FAZ1 A0A091C886 A0A091C886 A0A0A7U264 A0A0A7U264
      (148 more...)
      Trehalose-phosphatase. [EC: 3.1.3.12]
      Trehalose 6-phosphate + H(2)O = trehalose + phosphate.
        		 92 A0A045IRJ9 A0A045IRJ9 A0A059MGK3 A0A059MGK3 A0A0E2Z2D0 A0A0E2Z2D0 A0A0G4E0R1 A0A0G4E0R1 A0A0H3LAJ5 A0A0H3LAJ5
        (82 more...)
        Alpha,alpha-trehalase. [EC: 3.2.1.28]
        Alpha,alpha-trehalose + H(2)O = beta-D-glucose + alpha-D-glucose.
        • The enzyme is an anomer-inverting glucosidase that catalyzes the hydrolysis of the alpha-glucosidic O-linkage of alpha,alpha- trehalose, releasing initially equimolar amounts of alpha- and beta- D-glucose.
        • It is widely distributed in microorganisms, plants, invertebrates and vertebrates.
        		 68 A0A045IRJ9 A0A045IRJ9 A0A0G4E0R1 A0A0G4E0R1 A0A0H3LAJ5 A0A0H3LAJ5 A0A0H3MEE9 A0A0H3MEE9 A0A0H3P6N6 A0A0H3P6N6
        (58 more...)
        Beta-phosphoglucomutase. [EC: 5.4.2.6]
        Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
        • The enzyme is able to autophosphorylate itself with its substrate beta-D-glucose 1-phosphate.
        • Although this is a slow reaction, only a single turnover is required for activation.
        • Once the phosphorylated enzyme is formed, it generates the reaction intermediate beta-D-glucose 1,6-bisphosphate, which can be used to phosphorylate the enzyme in subsequent cycles.
        • Cf. EC 5.4.2.2.
        		 46 A0A0S2DI44 A0A0S2DI44 A0A0S2FAN6 A0A0S2FAN6 A0A0S2FR94 A0A0S2FR94 A0A0S2G7P9 A0A0S2G7P9 B2GM32 B2GM32
        (36 more...)
        Nigerose phosphorylase. [EC: 2.4.1.279]
        3-O-alpha-D-glucopyranosyl-D-glucopyranose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
        • The enzymes from Clostridium phytofermentans is specific for nigerose.
        • and shows only 0.5% relative activity with kojibiose (cf. EC 2.4.1.230).
        		 8 A0A0U5P2S1 A0A0U5P2S1 A0A1D8AVC9 A0A1D8AVC9 A0A1J5S7S8 A0A1J5S7S8 A9KT32 A9KT32
        1,2-alpha-glucosylglycerol phosphorylase. [EC: 2.4.1.332]
        2-O-alpha-D-glucopyranosyl-glycerol + phosphate = beta-D-glucose 1-phosphate + glycerol.
        • The enzyme has been isolated from the bacterium Bacillus selenitireducens.
        • In the absence of glycerol the enzyme produces alpha-D-glucopyranose and phosphate from beta-D-glucopyranose 1-phosphate.
        • In this reaction the glucosyl residue is transferred to a water molecule with an inversion of the anomeric conformation.
        		 2 D6XZ22 D6XZ22
        3-O-alpha-D-glucosyl-L-rhamnose phosphorylase. [EC: 2.4.1.282]
        3-O-alpha-D-glucopyranosyl-L-rhamnopyranose + phosphate = L-rhamnopyranose + beta-D-glucose 1-phosphate.
        • The enzyme does not phosphorylate alpha,alpha-trehalose, kojibiose, nigerose, or maltose.
        • In the reverse phosphorolysis reaction the enzyme is specific for L-rhamnose as acceptor and beta-D-glucose 1-phosphate as donor.
        		 2 A9KM56 A9KM56