The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 146013: Mitochondria fission 1 protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q9Y3D6 (/IPI)
Receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q9CQ92 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9Y3D6 (/IPI)
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P84817 (/IDA)

There are 63 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
4 P84817 (/ISS) Q3T0I5 (/ISS) Q9CQ92 (/ISS) Q9USZ8 (/ISS)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
3 P40515 (/IMP) Q9CQ92 (/IMP) Q9Y3D6 (/IMP)
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
3 P84817 (/ISS) Q3T0I5 (/ISS) Q9CQ92 (/ISS)
Positive regulation of mitochondrial fission GO:0090141
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
3 B7YZT2 (/IMP) B7YZT3 (/IMP) P84817 (/IMP)
Positive regulation of mitochondrial fission GO:0090141
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
3 P84817 (/ISS) Q3T0I5 (/ISS) Q9CQ92 (/ISS)
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
3 P84817 (/ISS) Q3T0I5 (/ISS) Q9CQ92 (/ISS)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
2 B7YZT2 (/IGI) B7YZT3 (/IGI)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
2 A5HUN3 (/IMP) Q9Y3D6 (/IMP)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
2 P84817 (/ISS) Q9CQ92 (/ISS)
Mitochondrial fragmentation involved in apoptotic process GO:0043653
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
2 P84817 (/IMP) Q9Y3D6 (/IMP)
Mitochondrial fragmentation involved in apoptotic process GO:0043653
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
2 P84817 (/ISS) Q9CQ92 (/ISS)
Positive regulation of mitochondrial fission GO:0090141
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
2 P40515 (/IDA) Q9Y3D6 (/IDA)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
1 Q9Y3D6 (/IDA)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
1 P40515 (/IGI)
Mitochondrial fission GO:0000266
The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
1 Q9CQ92 (/ISO)
Mitophagy GO:0000422
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
1 Q9Y3D6 (/IDA)
Mitophagy GO:0000422
The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
1 Q9CQ92 (/ISO)
Chronological cell aging GO:0001300
The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.
1 P40515 (/IMP)
Release of cytochrome c from mitochondria GO:0001836
The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
1 Q9Y3D6 (/IMP)
Release of cytochrome c from mitochondria GO:0001836
The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
1 Q9CQ92 (/ISO)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
1 Q9Y3D6 (/IMP)
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
1 Q9CQ92 (/ISO)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
1 Q9USZ8 (/ISS)
Peroxisome organization GO:0007031
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
1 P40515 (/IMP)
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
1 Q9Y3D6 (/IMP)
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
1 Q9CQ92 (/ISO)
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
1 Q9Y3D6 (/IMP)
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
1 Q9CQ92 (/ISO)
Regulation of mitochondrion organization GO:0010821
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
1 Q9Y3D6 (/IMP)
Regulation of mitochondrion organization GO:0010821
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
1 Q9CQ92 (/ISO)
Response to muscle activity GO:0014850
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
1 P84817 (/IEP)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
1 Q9Y3D6 (/IDA)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
1 P40515 (/IGI)
Peroxisome fission GO:0016559
The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
1 Q9CQ92 (/ISO)
Negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471
Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.
1 Q9Y3D6 (/IMP)
Negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471
Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.
1 Q9CQ92 (/ISO)
Calcium-mediated signaling using intracellular calcium source GO:0035584
A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.
1 Q9Y3D6 (/IMP)
Calcium-mediated signaling using intracellular calcium source GO:0035584
A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.
1 Q9CQ92 (/ISO)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
1 Q9Y3D6 (/IMP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
1 Q9CQ92 (/ISO)
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
1 P84817 (/IMP)
Mitochondrial fragmentation involved in apoptotic process GO:0043653
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
1 Q9Y3D6 (/IDA)
Mitochondrial fragmentation involved in apoptotic process GO:0043653
The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
1 Q9CQ92 (/ISO)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P84817 (/IDA)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9Y3D6 (/IMP)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 Q9CQ92 (/ISO)
Positive regulation of mitochondrial calcium ion concentration GO:0051561
Any process that increases the concentration of calcium ions in mitochondria.
1 Q9Y3D6 (/IMP)
Positive regulation of mitochondrial calcium ion concentration GO:0051561
Any process that increases the concentration of calcium ions in mitochondria.
1 Q9CQ92 (/ISO)
Lipid homeostasis GO:0055088
Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
1 E9QGI1 (/IMP)
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
1 Q9Y3D6 (/IMP)
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
1 Q9CQ92 (/ISO)
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
1 P84817 (/IEP)
Cellular response to lipid GO:0071396
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
1 P84817 (/IEP)
Positive regulation of mitochondrial fission GO:0090141
Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
1 Q9CQ92 (/ISO)
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
1 Q9Y3D6 (/IDA)
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
1 Q9CQ92 (/ISO)
Cellular response to toxic substance GO:0097237
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
1 P84817 (/IEP)
Cellular response to peptide GO:1901653
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
1 P84817 (/IDA)
Cellular response to thapsigargin GO:1904579
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.
1 P84817 (/IMP)
Response to flavonoid GO:1905395
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.
1 P84817 (/IEP)
Response to hypobaric hypoxia GO:1990910
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).
1 P84817 (/IEP)
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
1 Q9Y3D6 (/IMP)
Positive regulation of intrinsic apoptotic signaling pathway GO:2001244
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
1 Q9CQ92 (/ISO)

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P84817 (/IDA) Q9CQ92 (/IDA) Q9Y3D6 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
3 P40515 (/IDA) P84817 (/IDA) Q9Y3D6 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
3 Q3T0I5 (/ISS) Q9CQ92 (/ISS) Q9Y3D6 (/ISS)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
2 P40515 (/IDA) Q20291 (/IDA)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
2 B7YZT2 (/ISS) B7YZT3 (/ISS)
Integral component of peroxisomal membrane GO:0005779
The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P84817 (/ISS) Q9CQ92 (/ISS)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P84817 (/IDA) Q9Y3D6 (/IDA)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P84817 (/ISS) Q9CQ92 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9USZ8 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9CQ92 (/ISO)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
1 Q9USZ8 (/ISS)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 Q9CQ92 (/ISO)
Peroxisomal membrane GO:0005778
The lipid bilayer surrounding a peroxisome.
1 P84817 (/IDA)
Integral component of peroxisomal membrane GO:0005779
The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9Y3D6 (/IDA)
Integral component of peroxisomal membrane GO:0005779
The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9CQ92 (/ISO)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9Y3D6 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9CQ92 (/ISO)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9CQ92 (/ISO)
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9Y3D6 (/NAS)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q9Y3D6 (/IDA)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q9CQ92 (/ISO)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 Q9USZ8 (/NAS)