The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 145142: Tetratricopeptide repeat protein 30A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
6 A4IHR1 (/ISS) A4IHR1 (/ISS) Q16JL4 (/ISS) Q6INU8 (/ISS) Q6INU8 (/ISS) Q7PRA4 (/ISS)
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
2 A7YE96 (/IMP) A7YE96 (/IMP)
Tubulin-glycine ligase activity GO:0070738
Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.
2 A7YE96 (/IMP) A7YE96 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8N4P2 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein polyglutamylation GO:0018095
The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.
6 A4IHR1 (/ISS) A4IHR1 (/ISS) Q16JL4 (/ISS) Q6INU8 (/ISS) Q6INU8 (/ISS) Q7PRA4 (/ISS)
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
6 A4IHR1 (/ISS) A4IHR1 (/ISS) Q16JL4 (/ISS) Q6INU8 (/ISS) Q6INU8 (/ISS) Q7PRA4 (/ISS)
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
2 A7YE96 (/IGI) A7YE96 (/IGI)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
2 A7YE96 (/IMP) A7YE96 (/IMP)
Protein polyglutamylation GO:0018095
The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.
2 A7YE96 (/IMP) A7YE96 (/IMP)
Intraciliary anterograde transport GO:0035720
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
2 Q99J38 (/IC) Q99J38 (/IC)
Opsin transport GO:0036372
The directed movement of an opsin (a G-protein coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
2 A7YE96 (/IGI) A7YE96 (/IGI)
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
2 A2AKQ8 (/IC) Q9CY00 (/IC)
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
2 A7YE96 (/IMP) A7YE96 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
2 A7YE96 (/IGI) A7YE96 (/IGI)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
2 A7YE96 (/IMP) A7YE96 (/IMP)
Intraciliary anterograde transport GO:0035720
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
1 Q580S6 (/IMP)
Intraciliary anterograde transport GO:0035720
The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
1 E9ADL7 (/ISO)
Intraciliary transport involved in cilium assembly GO:0035735
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
1 Q580S6 (/IMP)
Intraciliary transport involved in cilium assembly GO:0035735
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
1 E9ADL7 (/ISO)
Intraciliary transport involved in cilium assembly GO:0035735
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
1 Q8N4P2 (/TAS)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Axonemal microtubule GO:0005879
A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.
6 A4IHR1 (/ISS) A4IHR1 (/ISS) Q16JL4 (/ISS) Q6INU8 (/ISS) Q6INU8 (/ISS) Q7PRA4 (/ISS)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
6 A4IHR1 (/ISS) A4IHR1 (/ISS) Q16JL4 (/ISS) Q6INU8 (/ISS) Q6INU8 (/ISS) Q7PRA4 (/ISS)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
4 A7YE96 (/IDA) A7YE96 (/IDA) Q99J38 (/IDA) Q99J38 (/IDA)
Intraciliary transport particle B GO:0030992
The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.
4 A2AKQ8 (/IDA) Q99J38 (/IDA) Q99J38 (/IDA) Q9CY00 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q99J38 (/IDA) Q99J38 (/IDA)
Axonemal microtubule GO:0005879
A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.
2 A7YE96 (/IDA) A7YE96 (/IDA)
Motile cilium GO:0031514
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
2 A7YE96 (/IDA) A7YE96 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q8N4P2 (/TAS)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
1 Q9CY00 (/ISO)
Ciliary tip GO:0097542
Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
1 Q8N4P2 (/TAS)