The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Leucine-rich Repeat Variant
".
FunFam 69540: Deoxyhypusine hydroxylase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
|
9 | Q17949 (/ISS) Q297S2 (/ISS) Q556G4 (/ISS) Q5PPJ4 (/ISS) Q5ZIP3 (/ISS) Q66KT3 (/ISS) Q7ZUX6 (/ISS) Q99LN9 (/ISS) Q9V9U4 (/ISS) |
|
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
|
3 | Q4Q901 (/ISO) Q99LN9 (/ISO) Q9P6K9 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P47120 (/IPI) Q9BU89 (/IPI) |
|
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
|
2 | P47120 (/IMP) Q9BU89 (/IMP) |
|
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
|
1 | D9IFD5 (/IDA) |
|
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
|
1 | Q4Q901 (/ISO) |
|
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
|
1 | Q9BU89 (/EXP) |
|
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
|
1 | P47120 (/IDA) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
|
9 | Q17949 (/ISS) Q297S2 (/ISS) Q556G4 (/ISS) Q5PPJ4 (/ISS) Q5ZIP3 (/ISS) Q66KT3 (/ISS) Q7ZUX6 (/ISS) Q99LN9 (/ISS) Q9V9U4 (/ISS) |
|
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
|
3 | P47120 (/IMP) Q99LN9 (/IMP) Q9BU89 (/IMP) |
|
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
|
2 | D9IFD5 (/IDA) P47120 (/IDA) |
|
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
|
2 | Q99LN9 (/ISO) Q9P6K9 (/ISO) |
|
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
|
1 | P47120 (/IGI) |
|
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
|
1 | P47120 (/IMP) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q9V9U4 (/IMP) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q4Q901 (/ISO) |
|
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
|
1 | Q9BU89 (/TAS) |
|
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
|
1 | Q9V9U4 (/IMP) |
|
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
|
1 | Q9V9U4 (/IMP) |
|
Filamentous growth of a population of unicellular organisms in response to neutral pH GO:0036178
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
|
1 | Q59Z14 (/IMP) |
|
Single-species biofilm formation on inanimate substrate GO:0044011
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
|
1 | Q59Z14 (/IMP) |
|
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q59Z14 (/IMP) |
|
Hypusine metabolic process GO:0046516
The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.
|
1 | D9IFD5 (/IDA) |
|
Mitochondrion distribution GO:0048311
Any process that establishes the spatial arrangement of mitochondria between and within cells.
|
1 | Q9P6K9 (/IGI) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9P6K9 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q17949 (/IC) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9P6K9 (/IDA) |
|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
1 | Q9V9U4 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9P6K9 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9BU89 (/TAS) |