The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Bromodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4314: Protein kinase C-binding protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
9 A2A480 (/ISO) A2A481 (/ISO) A2A482 (/ISO) A2A483 (/ISO) A2A484 (/ISO) A2A485 (/ISO) E9Q8D1 (/ISO) Q3U1M7 (/ISO) Q3UH28 (/ISO)
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
9 A2A480 (/ISO) A2A481 (/ISO) A2A482 (/ISO) A2A483 (/ISO) A2A484 (/ISO) A2A485 (/ISO) E9Q8D1 (/ISO) Q3U1M7 (/ISO) Q3UH28 (/ISO)
Protein N-terminus binding GO:0047485
Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
3 A0A0G2K9F7 (/IPI) A8C4G9 (/IPI) Q5XI91 (/IPI)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 A8C4G9 (/IPI) Q9ULU4 (/IPI)
RNA polymerase II transcription corepressor activity GO:0001106
Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 D5LMF5 (/IDA)
RNA polymerase II transcription corepressor activity GO:0001106
Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 Q9ULU4 (/ISS)
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
1 Q9ULU4 (/IDA)
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
1 D5LMF5 (/IPI)
Repressing transcription factor binding GO:0070491
Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
1 Q9ULU4 (/ISS)
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
1 Q9ULU4 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
9 A2A480 (/ISO) A2A481 (/ISO) A2A482 (/ISO) A2A483 (/ISO) A2A484 (/ISO) A2A485 (/ISO) E9Q8D1 (/ISO) Q3U1M7 (/ISO) Q3UH28 (/ISO)
Negative regulation of transcription from RNA polymerase II promoter by histone modification GO:1903758
A histone modification that results in negative regulation of transcription from RNA polymerase II promoter.
9 A2A480 (/ISO) A2A481 (/ISO) A2A482 (/ISO) A2A483 (/ISO) A2A484 (/ISO) A2A485 (/ISO) E9Q8D1 (/ISO) Q3U1M7 (/ISO) Q3UH28 (/ISO)
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
3 A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) Q5XI91 (/IMP)
Positive regulation of dendritic spine development GO:0060999
Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
3 A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) Q5XI91 (/IMP)
Modulation of excitatory postsynaptic potential GO:0098815
Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
3 A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) Q5XI91 (/IMP)
Regulation of postsynaptic density protein 95 clustering GO:1902897
Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.
3 A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) Q5XI91 (/IMP)
Positive regulation of dendritic spine maintenance GO:1902952
Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.
3 A0A0G2K9F7 (/IMP) A8C4G9 (/IMP) Q5XI91 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 D5LMF5 (/IMP)
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
1 Q9ULU4 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter by histone modification GO:1903758
A histone modification that results in negative regulation of transcription from RNA polymerase II promoter.
1 Q9ULU4 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
9 A2A480 (/ISO) A2A481 (/ISO) A2A482 (/ISO) A2A483 (/ISO) A2A484 (/ISO) A2A485 (/ISO) E9Q8D1 (/ISO) Q3U1M7 (/ISO) Q3UH28 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) D5LMF5 (/IDA) Q5XI91 (/IDA) Q9ULU4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) Q5XI91 (/IDA)
Dendritic spine GO:0043197
A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including \thin\, \stubby\, \mushroom\, and \branched\, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
3 A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) Q5XI91 (/IDA)
Dendritic shaft GO:0043198
Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
3 A0A0G2K9F7 (/IDA) A8C4G9 (/IDA) Q5XI91 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9ULU4 (/ISS)