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CATH Superfamily 1.20.910.10

Heme oxygenase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Heme oxygenase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2938: Heme oxygenase 1, chloroplastic

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Transferred entry: 1.14.14.18. [EC: 1.14.99.3]
    		20 A0A076K090 A0A0B2P9P1 A0A0B2QU43 A0A0B2SHY8 B4F9L9 D3K943 D6QXI6 D9IWR7 E2JEI2 E5L882
    (10 more...)
    Heme oxygenase (biliverdin-producing). [EC: 1.14.14.18]
    Protoheme + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) = biliverdin + Fe(2+) + CO + 3 [oxidized NADPH--hemoprotein reductase] + 3 H(2)O.
    • This mammalian enzyme participates in the degradation of heme.
    • The terminal oxygen atoms that are incorporated into the carbonyl groups of pyrrole rings A and B of biliverdin are derived from two separate oxygen molecules.
    • The third oxygen molecule provides the oxygen atom that converts the alpha-carbon to CO.
    • The enzyme requires NAD(P)H and EC 1.6.2.4.
    • Cf. EC 1.14.15.20.
    • Formerly EC 1.14.99.3.
    		 8 A0A0E0HT79 A0A0E0PZV9 A0A178VP48 I1Q3G3 O48782 Q69XJ4 Q9C9L4 Q9LQC0