CATH Superfamily 1.20.900.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Enzyme?	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
3381	Guanine nucleotide exchange factor	6686	EC	3D	4d0nB01	-	83.1
3378	Guanine nucleotide exchange factor DBS	5713	EC	3D	1ntyA01	-	81.5
3368	Still life, isoform P	1127		3D	1foeA01	-	85.0
3296	Rho guanine nucleotide exchange factor 9	932	EC	3D	2dx1A02	-	94.5
3395	Breakpoint cluster region protein	703	EC		-	-	94.5
3308	FYVE, RhoGEF and PH domain-containing protein 4	664			-	-	83.4
3275	Rho guanine nucleotide exchange factor 10	506			-	-	84.0
3298	Rho guanine nucleotide exchange factor 7	435		3D	1by1A00	-	91.3
3264	Ras-specific guanine nucleotide-releasing factor 2	423	EC		-	-	89.3
3306	FERM, RhoGEF and pleckstrin domain-containing protein 1	408		3D	4gyvA00	-	92.1
3377	Rho guanine nucleotide exchange factor 37	397			-	-	87.4
3285	Son of sevenless 1	311		3D	1dbhA01	-	88.0
3312	Pleckstrin homology domain-containing family G member 5	309			-	-	82.4
3394	Rho guanine nucleotide exchange factor scd1	295	EC		-	-	96.9
2525	Rho guanine nucleotide exchange factor 33	286			-	-	48.1
535	Epithelial cell transforming sequence 2 oncoprotein	194			-	-	63.0
2301	Rho guanine nucleotide exchange factor 38	147			-	-	90.3
3261	Obscurin	144	EC		-	-	38.2
1660	Pleckstrin homology domain-containing family G member 1	137			-	-	50.3
3271	Dynamin-binding protein	127			-	-	59.7
1263	Guanine nucleotide exchange factor VAV2	117			-	-	51.6
2035	Alsin	108			-	-	66.2
767	Rho guanine nucleotide exchange factor 17	89			-	-	32.7
1090	FYVE, RhoGEF and PH domain-containing protein 6	85			-	-	26.9
3278	FYVE, RhoGEF and PH domain-containing protein 5	72		3D	3mpxA01	-	56.7
3289	Rho guanine nucleotide exchange factor 40	65			-	-	51.7
2173	Bud site selection protein 3	63			-	-	10.7
2271	Protein son of sevenless	59			-	-	62.6
2119	Protostome-specific GEF, isoform F	50			-	-	18.7
2145	Nuclear fusion protein FUS2	50			-	-	3.7
610	Pebble, isoform C	43			-	-	9.4
3279	Rho guanine nucleotide exchange factor 39	41			-	-	47.0
279	CG42674, isoform E	40			-	-	17.4
2251	Rho-type guanine nucleotide exchange factor, isoform A	37			-	-	16.0
518	YLR425Wp-like protein	30			-	-	6.1
1112	CG43658, isoform F	28			-	-	9.9
3288	ALS2 C-terminal like, isoform CRA_c	26			-	-	43.5
2776	CG30456, isoform D	24			-	-	22.6
2243	LD03170p	17			-	-	20.5
1335	Epithelial cell-transforming sequence 2 oncogene-like	15			-	-	20.0
3248	Intersectin 1 isoform 6	14			-	-	12.8
3402	CGEF-1, isoform b	13			-	-	80.8
2322	UNC-73, isoform e	10			-	-	10.7
650	Rho guanine nucleotide exchange factor 3	9			-	-	0.6
1848	GM10784	7			-	-	7.0
1000	EXC-5, isoform a	6			-	-	17.7
3390	Rho guanine nucleotide exchange factor gef1	4			-	-	56.6
2370	Guanine exchange factor for Rac 30	3			-	-	0.0
3286	RhoGEF domain-containing protein gxcH	2			-	-	27.7
897	ECT-2, isoform a	2			-	-	0.0
2649	Uncharacterized protein	2			-	-	5.4
2388	PIX-1, isoform b	2			-	-	0.0
1088	TAG-77, isoform a	1			-	-	0.0
583	Rac guanyl-nucleotide exchange factor	1			-	-	0.0
934	Rac guanine nucleotide exchange factor JJ	1			-	-	0.0
3136	RH56938p	1			-	-	0.0
56	Rac guanine nucleotide exchange factor B	1			-	-	0.0
396	GxcC	1			-	-	0.0
7	Guanine nucleotide exchange factor for RAS	1			-	-	0.0