The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Neurotransmitter-gated ion-channel transmembrane domain
".
FunFam 2653: Acetylcholine receptor subunit beta-type acr-2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
|
1 | P04755 (/ISS) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of oviposition GO:0046662
Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
|
2 | P48181 (/IMP) Q27218 (/IMP) |
|
Regulation of muscle contraction GO:0006937
Any process that modulates the frequency, rate or extent of muscle contraction.
|
1 | P48181 (/IMP) |
|
Synaptic transmission, cholinergic GO:0007271
The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse using the neurotransmitter acetylcholine.
|
1 | P04755 (/IEP) |
|
Neuromuscular synaptic transmission GO:0007274
The process of communication from a neuron to a muscle, across a synapse.
|
1 | P48181 (/IDA) |
|
Positive regulation of acetylcholine secretion, neurotransmission GO:0014057
Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.
|
1 | P48181 (/IMP) |
|
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
|
1 | P48181 (/IMP) |
|
Regulation of locomotion GO:0040012
Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
|
1 | Q27218 (/IMP) |
|
Regulation of pharyngeal pumping GO:0043051
Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.
|
1 | P48181 (/IGI) |
|
Inorganic cation transmembrane transport GO:0098662
A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q93149 (/IDA) |
|
Inorganic cation transmembrane transport GO:0098662
A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q27218 (/IMP) |
|
Calcium ion import across plasma membrane GO:0098703
The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.
|
1 | Q93149 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
3 | P04755 (/IDA) P48181 (/IDA) Q27218 (/IDA) |
|
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
|
2 | P48181 (/IDA) Q27218 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
2 | P48181 (/IDA) Q27218 (/IDA) |
|
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
|
1 | P04755 (/ISS) |
|
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
1 | P48181 (/IDA) |
