The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6718: PAR domain protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
12 M9PBV3 (/IDA) M9PEP3 (/IDA) M9PEX4 (/IDA) Q24217 (/IDA) Q5U8V5 (/IDA) Q7KKI2 (/IDA) Q8IQ98 (/IDA) Q8IQ99 (/IDA) Q8SZT1 (/IDA) Q9TVQ4 (/IDA)
(2 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
12 M9PBV3 (/ISS) M9PEP3 (/ISS) M9PEX4 (/ISS) Q24217 (/ISS) Q5U8V5 (/ISS) Q7KKI2 (/ISS) Q8IQ98 (/ISS) Q8IQ99 (/ISS) Q8SZT1 (/ISS) Q9TVQ4 (/ISS)
(2 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
12 M9PBV3 (/IDA) M9PEP3 (/IDA) M9PEX4 (/IDA) Q24217 (/IDA) Q5U8V5 (/IDA) Q7KKI2 (/IDA) Q8IQ98 (/IDA) Q8IQ99 (/IDA) Q8SZT1 (/IDA) Q9TVQ4 (/IDA)
(2 more)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q24217 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
12 M9PBV3 (/IMP) M9PEP3 (/IMP) M9PEX4 (/IMP) Q24217 (/IMP) Q5U8V5 (/IMP) Q7KKI2 (/IMP) Q8IQ98 (/IMP) Q8IQ99 (/IMP) Q8SZT1 (/IMP) Q9TVQ4 (/IMP)
(2 more)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
12 M9PBV3 (/IMP) M9PEP3 (/IMP) M9PEX4 (/IMP) Q24217 (/IMP) Q5U8V5 (/IMP) Q7KKI2 (/IMP) Q8IQ98 (/IMP) Q8IQ99 (/IMP) Q8SZT1 (/IMP) Q9TVQ4 (/IMP)
(2 more)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
12 M9PBV3 (/IDA) M9PEP3 (/IDA) M9PEX4 (/IDA) Q24217 (/IDA) Q5U8V5 (/IDA) Q7KKI2 (/IDA) Q8IQ98 (/IDA) Q8IQ99 (/IDA) Q8SZT1 (/IDA) Q9TVQ4 (/IDA)
(2 more)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
12 M9PBV3 (/IGI) M9PEP3 (/IGI) M9PEX4 (/IGI) Q24217 (/IGI) Q5U8V5 (/IGI) Q7KKI2 (/IGI) Q8IQ98 (/IGI) Q8IQ99 (/IGI) Q8SZT1 (/IGI) Q9TVQ4 (/IGI)
(2 more)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
12 M9PBV3 (/IMP) M9PEP3 (/IMP) M9PEX4 (/IMP) Q24217 (/IMP) Q5U8V5 (/IMP) Q7KKI2 (/IMP) Q8IQ98 (/IMP) Q8IQ99 (/IMP) Q8SZT1 (/IMP) Q9TVQ4 (/IMP)
(2 more)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
12 M9PBV3 (/TAS) M9PEP3 (/TAS) M9PEX4 (/TAS) Q24217 (/TAS) Q5U8V5 (/TAS) Q7KKI2 (/TAS) Q8IQ98 (/TAS) Q8IQ99 (/TAS) Q8SZT1 (/TAS) Q9TVQ4 (/TAS)
(2 more)
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
12 M9PBV3 (/IMP) M9PEP3 (/IMP) M9PEX4 (/IMP) Q24217 (/IMP) Q5U8V5 (/IMP) Q7KKI2 (/IMP) Q8IQ98 (/IMP) Q8IQ99 (/IMP) Q8SZT1 (/IMP) Q9TVQ4 (/IMP)
(2 more)
Growth GO:0040007
The increase in size or mass of an entire organism, a part of an organism or a cell.
12 M9PBV3 (/IMP) M9PEP3 (/IMP) M9PEX4 (/IMP) Q24217 (/IMP) Q5U8V5 (/IMP) Q7KKI2 (/IMP) Q8IQ98 (/IMP) Q8IQ99 (/IMP) Q8SZT1 (/IMP) Q9TVQ4 (/IMP)
(2 more)
DNA endoreduplication GO:0042023
Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
12 M9PBV3 (/IMP) M9PEP3 (/IMP) M9PEX4 (/IMP) Q24217 (/IMP) Q5U8V5 (/IMP) Q7KKI2 (/IMP) Q8IQ98 (/IMP) Q8IQ99 (/IMP) Q8SZT1 (/IMP) Q9TVQ4 (/IMP)
(2 more)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q24217 (/IDA)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
12 M9PBV3 (/IDA) M9PEP3 (/IDA) M9PEX4 (/IDA) Q24217 (/IDA) Q5U8V5 (/IDA) Q7KKI2 (/IDA) Q8IQ98 (/IDA) Q8IQ99 (/IDA) Q8SZT1 (/IDA) Q9TVQ4 (/IDA)
(2 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q24217 (/IC)
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