View in Gene3D

CATH Superfamily 1.20.20.10

F1F0 ATP synthase subunit C

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
F1F0 ATP synthase subunit C
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1411: ATP synthase F0 subunit 9

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
H(+)-transporting two-sector ATPase. [EC: 3.6.3.14]
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
  • A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.
  • Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (F(o), V(o), A(o)) and a cytoplasmic-compartment sector (F(1), V(1), A(1)).
  • The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.
  • All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.
  • Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.
  • This movement is driven by the H(+) electrochemical potential gradient.
  • The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.
  • Formerly EC 3.6.1.34.
 28 A0A061ILJ0 A0A061ILJ0 B5B7Q4 B5B7Q4 B7Q6S9 B7Q6S9 C1LAX9 C1LAX9 C1LU83 C1LU83
(18 more...)
Proton-exporting ATPase. [EC: 3.6.3.6]
ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Generates an electrochemical potential gradient of protons across the plasma membrane.
  • Formerly EC 3.6.1.35.
 12 B3P7R7 B3P7R7 E3TC28 E3TC28 E3TEK0 E3TEK0 E3TG74 E3TG74 H0RNC4 H0RNC4
(2 more...)
Isocitrate dehydrogenase (NADP(+)). [EC: 1.1.1.42]
Isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.
  • Unlike EC 1.1.1.41, oxalosuccinate can be used as a substrate.
  • In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD(+)-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP(+)-linked enzyme that is found in both mitochondria and cytoplasm.
  • The enzyme from some species can also use NAD(+) but much more slowly.
 6 E3TC28 E3TC28 E3TEK0 E3TEK0 E3TG74 E3TG74
CATH-Gene3D is a Global Biodata Core Resource Learn more...