The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ABC transporter type 1, transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 26693: HlyB/MsbA family ABC transporter

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Peptide-transporting ATPase. [EC: 3.6.3.43]
ATP + H(2)O + peptide(In) = ADP + phosphate + peptide(Out).
  • A family of enzymes that exports alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.
86 A0A068QPM5 A0A068QQC9 A0A068R444 A0A068R7D5 A0A075KCA0 A0A077MQL0 A0A077N1H7 A0A077NME3 A0A077NP94 A0A077NYQ2
(76 more...)
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
10 A0A0N0Z6R7 A0A0N1KI96 A0A1B7HKQ9 A0A1B7HUP2 A0A1B7I1T5 A0A1B7IVG0 A0A1B7K0P6 A0A1B7K632 K6Q0Z7 K6RNK3
Nucleoside-triphosphate phosphatase. [EC: 3.6.1.15]
NTP + H(2)O = NDP + phosphate.
  • The enzyme is found in eukaryotes and thermophilic bacteria, but appears to be absent from mesophilic bacteria.
  • Also hydrolyzes nucleoside diphosphates, thiamine diphosphate and FAD.
  • The enzyme from the plant Pisum sativum (garden pea) is regulated by calmodulin.
8 A0A0N0Z6R7 A0A0N1KI96 A0A1B7HKQ9 A0A1B7HUP2 A0A1B7I1T5 A0A1B7IVG0 A0A1B7K0P6 A0A1B7K632
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