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CATH Superfamily 1.20.1560.10

ABC transporter type 1, transmembrane domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ABC transporter type 1, transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 26431: Type I secretion system ATPase

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Peptide-transporting ATPase. [EC: 3.6.3.43]
ATP + H(2)O + peptide(In) = ADP + phosphate + peptide(Out).
  • A family of enzymes that exports alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.
 13 A0A077MYU8 A0A077NAC9 A0A077NAX1 A0A077NYF7 A0A077P5C5 A0A077PK62 A0A077PRP9 A0A077QHQ4 A0A0A8NXL3 A0A0R4CZN8
(3 more...)
Xenobiotic-transporting ATPase. [EC: 3.6.3.44]
ATP + H(2)O + xenobiotic(In) = ADP + phosphate + xenobiotic(Out).
  • Enzymes of Gram-positive bacteria and eukaryotic cells that export a number of drugs, with unusual specificity, covering various groups of unrelated substances, while ignoring some that are closely related structurally.
  • Several distinct enzymes may be present in a single eukaryotic cell.
  • Many of them transport glutathione conjugates with drugs.
  • Some also show some 'flippase' (EC 3.6.3.1) activity.
  • Formerly EC 3.6.3.45.
 2 F9ZF29 W6VJZ6
Serralysin. [EC: 3.4.24.40]
Preferential cleavage of bonds with hydrophobic residues in P1'.
  • An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.
  • There is broad specificity in cleavage of the insulin B chain, with some species variations.
  • The pH optimum for digesting various proteins is about 9-10.
  • Belongs to peptidase family M10A.
  • Formerly EC 3.4.24.4.
 1 K9URH4
Adenosinetriphosphatase. [EC: 3.6.1.3]
ATP + H(2)O = ADP + phosphate.
  • Many enzymes previously listed under this number are now listed separately as EC 3.6.1.32 to EC 3.6.1.39.
  • The remaining enzymes, not separately listed on the basis of some function coupled with hydrolyzes of ATP, include enzymes dependent on Ca(2+), Mg(2+), anions, H(+) or DNA.
  • Formerly EC 3.6.1.4.
 1 A0A1L9EUM2
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