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CATH Superfamily 1.20.1300.10

Fumarate reductase/succinate dehydrogenase, transmembrane subunit

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Fumarate reductase/succinate dehydrogenase, transmembrane subunit
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2944: Succinate dehydrogenase cytochrome b556 subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Succinate dehydrogenase (quinone). [EC: 1.3.5.1]
Succinate + a quinone = fumarate + a quinol.
  • The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of many aerobic or facultative bacteria.
  • It catalyzes succinate oxidation in the citric acid cycle and transfers the electrons to quinones in the membrane, thus constituting a part of the aerobic respiratory chain (known as complex II).
  • In vivo the enzyme uses the quinone found in the organism - eukaryotic enzymes utilize ubiquinone, bacterial enzymes utilize ubiquinone or menaquinone, and archaebacterial enzymes from the Sulfolobus genus use caldariellaquinone.
  • Cf. EC 1.3.5.4.
 948 A0A010QBR7 A0A010QBR7 A0A022PFG4 A0A022PFG4 A0A023E3G4 A0A023E3G4 A0A023VB92 A0A023VB92 A0A025CFK8 A0A025CFK8
(938 more...)
Deleted entry. [EC: 1.3.99.1]
    		162 A0A061CRX2 A0A061CRX2 A0A075PI46 A0A075PI46 A0A077MY97 A0A077MY97 A0A077NFU7 A0A077NFU7 A0A077NZ41 A0A077NZ41
    (152 more...)
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