The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
This superfamily represents the alpha subunit of the F-actin capping protein (CAPZA), a protein of about 280 amino acid residues whose sequence is well conserved in eukaryotic species PMID:1711931. In Drosophila mutations in the alpha and beta subunits cause actin accumulation and subsequent retinal degeneration PMID:16143599. In humans CAPZA is part of the WASH complex that controls the fission of endosomes PMID:19922875.
Structures | |
---|---|
Domains: | 33 |
Domain clusters (>95% seq id): | 2 |
Domain clusters (>35% seq id): | 1 |
Unique PDBs: | 16 |
Alignments | |
Structural Clusters (5A): | 1 |
Structural Clusters (9A): | 1 |
FunFam Clusters: | 0 |
Function | |
Unique EC: | 2 |
Unique GO: | 52 |
Taxonomy | |
Unique Species: | 1098 |