The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Arfaptin homology (AH) domain/BAR domain
".
FunFam 4553: F-BAR domain only protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
4 | D3ZYR1 (/ISS) Q0JRZ9 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) |
|
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
|
4 | D3ZYR1 (/ISS) Q0JRZ9 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) |
|
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
4 | D3ZYR1 (/ISS) Q0JRZ9 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
3 | O14526 (/IPI) Q0JRZ9 (/IPI) Q3UQN2 (/IPI) |
|
Phospholipid binding GO:0005543
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
|
3 | A0A0B4KFZ2 (/ISM) Q6AWD5 (/ISM) Q9VHC4 (/ISM) |
|
AP-2 adaptor complex binding GO:0035612
Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
|
3 | A0A0B4KFZ2 (/ISS) Q6AWD5 (/ISS) Q9VHC4 (/ISS) |
|
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
|
1 | Q3UQN2 (/IDA) |
|
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
|
1 | Q3UQN2 (/IDA) |
|
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
1 | Q3UQN2 (/IDA) |
|
AP-2 adaptor complex binding GO:0035612
Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
|
1 | O14526 (/IDA) |
|
AP-2 adaptor complex binding GO:0035612
Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
|
1 | Q8K285 (/ISO) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Clathrin-dependent endocytosis GO:0072583
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
|
9 | A0A0B4KFZ2 (/ISS) D3ZYR1 (/ISS) E7FBF7 (/ISS) Q3UQN2 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) Q6AWD5 (/ISS) Q8K285 (/ISS) Q9VHC4 (/ISS) |
|
Clathrin coat assembly GO:0048268
The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
|
6 | D3ZYR1 (/ISS) E7FBF7 (/ISS) Q3UQN2 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) Q8K285 (/ISS) |
|
Membrane invagination GO:0010324
The infolding of a membrane.
|
4 | D3ZYR1 (/ISS) Q0JRZ9 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) |
|
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
4 | D3ZYR1 (/ISS) Q0JRZ9 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
3 | A0A0R4IA99 (/IGI) A0A0R4IJ14 (/IGI) K7DXX1 (/IGI) |
|
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
|
3 | A0A0R4IA99 (/IMP) A0A0R4IJ14 (/IMP) K7DXX1 (/IMP) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
3 | A0A0R4IA99 (/IGI) A0A0R4IJ14 (/IGI) K7DXX1 (/IGI) |
|
Clathrin coat assembly GO:0048268
The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
|
2 | O14526 (/IMP) Q0JRZ9 (/IMP) |
|
Clathrin coat assembly GO:0048268
The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
|
2 | Q3UQN2 (/ISO) Q8K285 (/ISO) |
|
Synaptic vesicle endocytosis GO:0048488
Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
|
2 | D3ZYR1 (/IGI) Q3UQN2 (/IGI) |
|
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
2 | O14526 (/TAS) Q0JRZ9 (/TAS) |
|
Clathrin-dependent endocytosis GO:0072583
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
|
2 | O14526 (/IMP) Q0JRZ9 (/IMP) |
|
Clathrin-dependent endocytosis GO:0072583
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
|
2 | Q3UQN2 (/ISO) Q8K285 (/ISO) |
|
Membrane invagination GO:0010324
The infolding of a membrane.
|
1 | Q3UQN2 (/IDA) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
1 | Q502I9 (/IMP) |
|
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q3UQN2 (/IMP) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | A0A0B4KFZ2 (/ISS) D3ZYR1 (/ISS) E7FBF7 (/ISS) Q0JRZ9 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) Q6AWD5 (/ISS) Q8K285 (/ISS) Q9VHC4 (/ISS) |
|
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
|
8 | A0A0B4KFZ2 (/ISS) D3ZYR1 (/ISS) E7FBF7 (/ISS) Q502I9 (/ISS) Q5R807 (/ISS) Q6AWD5 (/ISS) Q8K285 (/ISS) Q9VHC4 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
5 | A0A0R4IA99 (/IDA) A0A0R4IJ14 (/IDA) K7DXX1 (/IDA) O14526 (/IDA) Q3UQN2 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | A0A0C3SFZ9 (/IDA) M0QZI3 (/IDA) O14526 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | A0A0B4KFZ2 (/IDA) Q6AWD5 (/IDA) Q9VHC4 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | A0A0C3SFZ9 (/IDA) M0QZI3 (/IDA) O14526 (/IDA) |
|
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
|
3 | O14526 (/IDA) Q0JRZ9 (/IDA) Q3UQN2 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | O14526 (/TAS) Q0JRZ9 (/TAS) |
|
Clathrin-coated pit GO:0005905
A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
|
2 | Q3UQN2 (/ISO) Q8K285 (/ISO) |
|
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
|
2 | Q0JRZ9 (/IDA) Q3UQN2 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8K285 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8K285 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q8K285 (/ISO) |
|
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
|
1 | Q3UQN2 (/ISO) |
|
Presynaptic endocytic zone membrane GO:0098835
The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release.
|
1 | D3ZYR1 (/IDA) |