CATH Superfamily 1.20.1250.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 8095: Interleukin 13
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytokine activity GO:0005125
Functions to control the survival, growth, differentiation and effector function of tissues and cells.
|
1 | P35225 (/TAS) |
Interleukin-13 receptor binding GO:0005144
Interacting selectively and non-covalently with the interleukin-13 receptor.
|
1 | P42203 (/IPI) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P35225 (/IPI) |
There are 35 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of complement-dependent cytotoxicity GO:1903660
Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.
|
3 | B3GDZ5 (/IMP) P35225 (/IMP) Q95J68 (/IMP) |
Negative regulation of endothelial cell apoptotic process GO:2000352
Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.
|
3 | B3GDZ5 (/IMP) P35225 (/IMP) Q95J68 (/IMP) |
Microglial cell activation GO:0001774
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
|
1 | P42203 (/IMP) |
Positive regulation of immunoglobulin production GO:0002639
Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
|
1 | P42203 (/IDA) |
Positive regulation of immunoglobulin production GO:0002639
Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
|
1 | P20109 (/IGI) |
Positive regulation of immunoglobulin production GO:0002639
Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
|
1 | P20109 (/IMP) |
Movement of cell or subcellular component GO:0006928
The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
|
1 | P35225 (/TAS) |
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | P20109 (/IMP) |
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
1 | P35225 (/TAS) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | P35225 (/NAS) |
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
1 | P35225 (/IC) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
1 | P42203 (/IEP) |
Regulation of proton transport GO:0010155
Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P42203 (/IDA) |
Positive regulation of B cell proliferation GO:0030890
Any process that activates or increases the rate or extent of B cell proliferation.
|
1 | P42203 (/IDA) |
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
1 | P42203 (/IEP) |
Positive regulation of connective tissue growth factor production GO:0032723
Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.
|
1 | P42203 (/IDA) |
Negative regulation of NAD(P)H oxidase activity GO:0033861
Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.
|
1 | P42203 (/IMP) |
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
|
1 | P42203 (/IDA) |
Positive regulation of macrophage activation GO:0043032
Any process that stimulates, induces or increases the rate of macrophage activation.
|
1 | P20109 (/IMP) |
Positive regulation of ion transport GO:0043270
Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P42203 (/IDA) |
Positive regulation of mast cell degranulation GO:0043306
Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
|
1 | P20109 (/IGI) |
Positive regulation of mast cell degranulation GO:0043306
Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
|
1 | P20109 (/IMP) |
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
1 | P42203 (/IEP) |
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
1 | P42203 (/IDA) |
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
|
1 | P42203 (/IDA) |
Positive regulation of release of sequestered calcium ion into cytosol GO:0051281
Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
|
1 | P42203 (/IDA) |
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
1 | P42203 (/IEP) |
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | P20109 (/IDA) |
Negative regulation of transforming growth factor beta production GO:0071635
Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.
|
1 | P42203 (/IDA) |
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
|
1 | P42203 (/IMP) |
Negative regulation of lung ciliated cell differentiation GO:1901247
Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.
|
1 | P35225 (/NAS) |
Positive regulation of lung goblet cell differentiation GO:1901251
Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.
|
1 | P35225 (/NAS) |
Negative regulation of complement-dependent cytotoxicity GO:1903660
Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.
|
1 | P20109 (/ISO) |
Positive regulation of pancreatic stellate cell proliferation GO:2000231
Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.
|
1 | P42203 (/IDA) |
Negative regulation of endothelial cell apoptotic process GO:2000352
Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.
|
1 | P20109 (/ISO) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P20109 (/IDA) P42203 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P35225 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P20109 (/ISO) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P35225 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P35225 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P20109 (/IDA) |
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | P20109 (/IDA) |