The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Voltage-gated potassium channels. Chain C
".
FunFam 4260: Putative voltage-gated potassium channel
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 43 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
14 |
A0A0R4IEI6 (/IDA)
B3DHL9 (/IDA)
B3DJX4 (/IDA)
E9QJ94 (/IDA)
F1RBF8 (/IDA)
F1RBP0 (/IDA)
F6NT38 (/IDA)
O08962 (/IDA)
O18965 (/IDA)
O35219 (/IDA)
(4 more) |
|
Inward rectifier potassium channel activity GO:0005242
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
|
5 | O08962 (/IDA) O35219 (/IDA) O54852 (/IDA) O54853 (/IDA) Q12809 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O08962 (/IPI) O95259 (/IPI) Q02280 (/IPI) Q12809 (/IPI) Q63472 (/IPI) |
|
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
|
4 | B3DJX4 (/IDA) E9QJ94 (/IDA) F6NT38 (/IDA) O08962 (/IDA) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
4 | O95259 (/IDA) Q12809 (/IDA) Q60603 (/IDA) Q63472 (/IDA) |
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
4 | B3DJX4 (/ISS) E9QJ94 (/ISS) F6NT38 (/ISS) O44164 (/ISS) |
|
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
|
3 | B3DJX4 (/IMP) E9QJ94 (/IMP) F6NT38 (/IMP) |
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
3 | A0A0B4LGW2 (/NAS) A1ZB14 (/NAS) Q7JPB9 (/NAS) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Voltage-gated cation channel activity GO:0022843
Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
3 | A0A0B4LGW2 (/ISS) A1ZB14 (/ISS) Q7JPB9 (/ISS) |
|
Phosphatidylinositol bisphosphate binding GO:1902936
Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
2 | Q02280 (/TAS) Q9UQ05 (/TAS) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
2 | O35219 (/ISO) Q60603 (/ISO) |
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
2 | O08962 (/IDA) O54852 (/IDA) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
2 | O44164 (/IPI) Q63472 (/IPI) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | Q63472 (/IPI) Q9EPI9 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q63472 (/IPI) Q9EPI9 (/IPI) |
|
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
2 | O08962 (/IPI) Q12809 (/IPI) |
|
Transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
|
1 | Q9QWS8 (/IMP) |
|
Inward rectifier potassium channel activity GO:0005242
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
|
1 | O35219 (/ISO) |
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q9QWS8 (/IMP) |
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | O35219 (/ISO) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
1 | Q12809 (/IGI) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
1 | O95259 (/TAS) |
|
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | O54853 (/TAS) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
1 | Q63472 (/IDA) |
|
Voltage-gated cation channel activity GO:0022843
Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q02280 (/IDA) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q12809 (/IPI) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | O35219 (/ISO) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q63472 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q12809 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | O35219 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q12809 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | O35219 (/ISO) |
|
C3HC4-type RING finger domain binding GO:0055131
Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.
|
1 | Q12809 (/IPI) |
|
C3HC4-type RING finger domain binding GO:0055131
Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.
|
1 | O35219 (/ISO) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q63472 (/IPI) |
|
Voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization GO:0086008
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q12809 (/IC) |
|
Scaffold protein binding GO:0097110
Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
|
1 | O35219 (/ISO) |
|
Voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:1902282
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | Q12809 (/IMP) |
|
Voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:1902282
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
1 | O35219 (/ISO) |
|
Phosphatidylinositol bisphosphate binding GO:1902936
Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
|
1 | O95259 (/IDA) |
|
Phosphatidylinositol bisphosphate binding GO:1902936
Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
|
1 | Q60603 (/ISO) |
There are 93 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
5 | O35219 (/IDA) O95259 (/IDA) Q12809 (/IDA) Q60603 (/IDA) Q63472 (/IDA) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
4 | A0A0R4IEI6 (/IMP) B3DHL9 (/IMP) F1RBF8 (/IMP) F1RBP0 (/IMP) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | O08962 (/IDA) O54852 (/IDA) O54853 (/IDA) Q02280 (/IDA) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | A0A0B4LGW2 (/ISS) A1ZB14 (/ISS) O44164 (/ISS) Q7JPB9 (/ISS) |
|
Hindbrain formation GO:0021576
The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
|
4 | A0A0R4IEI6 (/IMP) B3DHL9 (/IMP) F1RBF8 (/IMP) F1RBP0 (/IMP) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
4 | A0A0R4IEI6 (/IMP) B3DHL9 (/IMP) F1RBF8 (/IMP) F1RBP0 (/IMP) |
|
Regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.
|
4 | B3DJX4 (/IMP) E9QJ94 (/IMP) F6NT38 (/IMP) Q12809 (/IMP) |
|
Membrane repolarization during cardiac muscle cell action potential GO:0086013
The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
|
4 | B3DJX4 (/IMP) E9QJ94 (/IMP) F6NT38 (/IMP) Q12809 (/IMP) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | A0A0B4LGW2 (/NAS) A1ZB14 (/NAS) Q7JPB9 (/NAS) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | O95259 (/TAS) Q02280 (/TAS) Q9UQ05 (/TAS) |
|
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
|
3 | B3DJX4 (/IMP) E9QJ94 (/IMP) F6NT38 (/IMP) |
|
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
3 | O08962 (/IDA) O35219 (/IDA) Q12809 (/IDA) |
|
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
3 | O08962 (/IDA) O54852 (/IDA) O54853 (/IDA) |
|
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
|
3 | B3DJX4 (/IMP) E9QJ94 (/IMP) F6NT38 (/IMP) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Regulation of glucose metabolic process GO:0010906
Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
|
2 | A0A0B4LGW2 (/IMP) A1ZB14 (/IMP) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
2 | O18965 (/ISS) Q60603 (/ISS) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
2 | O35219 (/ISO) Q60603 (/ISO) |
|
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
1 | Q63472 (/IMP) |
|
Regulation of heart rate by hormone GO:0003064
The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
|
1 | Q12809 (/TAS) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | B3DHL9 (/IMP) |
|
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
1 | O44164 (/IMP) |
|
Regulation of muscle contraction GO:0006937
Any process that modulates the frequency, rate or extent of muscle contraction.
|
1 | G5EFJ9 (/IMP) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | O08962 (/IEP) |
|
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | B3DHL9 (/IMP) |
|
Myoblast fusion GO:0007520
A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
1 | O95259 (/TAS) |
|
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
|
1 | Q7JPB9 (/IMP) |
|
Sensory perception of smell GO:0007608
The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
|
1 | Q02280 (/NAS) |
|
Learning or memory GO:0007611
The acquisition and processing of information and/or the storage and retrieval of this information over time.
|
1 | Q02280 (/NAS) |
|
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
|
1 | Q02280 (/IMP) |
|
Mating behavior GO:0007617
The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.
|
1 | G5EFJ9 (/IMP) |
|
Courtship behavior GO:0007619
The behavioral interactions between organisms for the purpose of attracting sexual partners.
|
1 | Q02280 (/NAS) |
|
Courtship behavior GO:0007619
The behavioral interactions between organisms for the purpose of attracting sexual partners.
|
1 | Q02280 (/TAS) |
|
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | O54852 (/IEP) |
|
Flight behavior GO:0007629
The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
|
1 | Q02280 (/IMP) |
|
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
|
1 | O44164 (/IMP) |
|
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
|
1 | Q02280 (/NAS) |
|
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.
|
1 | Q8NCM2 (/IDA) |
|
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.
|
1 | Q920E3 (/ISO) |
|
Oviposition GO:0018991
The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
|
1 | O44164 (/IMP) |
|
Spinal cord development GO:0021510
The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
|
1 | O08962 (/IEP) |
|
Ion transmembrane transport GO:0034220
A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
1 | Q63472 (/IDA) |
|
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q12809 (/IDA) |
|
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | O35219 (/ISO) |
|
Perineurial glial growth GO:0042066
Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.
|
1 | Q02280 (/IGI) |
|
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
1 | O95259 (/IMP) |
|
Regulation of cell proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
1 | Q60603 (/ISO) |
|
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
1 | O35219 (/ISO) |
|
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
1 | Q9QWS8 (/IMP) |
|
Regulation of oviposition GO:0046662
Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
|
1 | G5EFJ9 (/NAS) |
|
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
1 | O95259 (/IMP) |
|
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
1 | Q60603 (/ISO) |
|
Behavioral response to ether GO:0048150
Any process that results in a change in the behavior of an organism as a result of an ether stimulus.
|
1 | Q02280 (/NAS) |
|
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q02280 (/IPI) |
|
Potassium ion homeostasis GO:0055075
Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
|
1 | Q12809 (/IDA) |
|
Potassium ion homeostasis GO:0055075
Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
|
1 | O35219 (/ISO) |
|
Cardiac muscle contraction GO:0060048
Muscle contraction of cardiac muscle tissue.
|
1 | Q12809 (/IMP) |
|
Cardiac muscle contraction GO:0060048
Muscle contraction of cardiac muscle tissue.
|
1 | O35219 (/ISO) |
|
Regulation of membrane repolarization GO:0060306
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.
|
1 | Q12809 (/IDA) |
|
Regulation of membrane repolarization GO:0060306
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.
|
1 | O35219 (/ISO) |
|
Regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.
|
1 | O35219 (/IDA) |
|
Regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307
Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.
|
1 | O35219 (/ISO) |
|
Cardiac conduction GO:0061337
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
|
1 | Q12809 (/TAS) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q63472 (/IDA) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | O95259 (/IMP) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q60603 (/ISO) |
|
Potassium ion export GO:0071435
The directed movement of potassium ions out of a cell or organelle.
|
1 | Q12809 (/IDA) |
|
Potassium ion export GO:0071435
The directed movement of potassium ions out of a cell or organelle.
|
1 | O35219 (/ISO) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | O18965 (/IMP) |
|
Ventricular cardiac muscle cell action potential GO:0086005
An action potential that occurs in a ventricular cardiac muscle cell.
|
1 | Q12809 (/IMP) |
|
Ventricular cardiac muscle cell action potential GO:0086005
An action potential that occurs in a ventricular cardiac muscle cell.
|
1 | O35219 (/ISO) |
|
Membrane depolarization during action potential GO:0086010
The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
|
1 | Q12809 (/IDA) |
|
Membrane depolarization during action potential GO:0086010
The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
|
1 | O35219 (/ISO) |
|
Membrane repolarization during action potential GO:0086011
The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
|
1 | Q12809 (/IDA) |
|
Membrane repolarization during action potential GO:0086011
The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
|
1 | O35219 (/ISO) |
|
Membrane repolarization during cardiac muscle cell action potential GO:0086013
The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
|
1 | O35219 (/ISO) |
|
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
|
1 | O35219 (/IDA) |
|
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
|
1 | Q12809 (/IMP) |
|
Regulation of heart rate by cardiac conduction GO:0086091
A cardiac conduction process that modulates the frequency or rate of heart contraction.
|
1 | O35219 (/ISO) |
|
Potassium ion export across plasma membrane GO:0097623
The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
1 | Q12809 (/IGI) |
|
Potassium ion export across plasma membrane GO:0097623
The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
1 | O35219 (/ISO) |
|
Membrane repolarization during ventricular cardiac muscle cell action potential GO:0098915
The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
|
1 | Q12809 (/IMP) |
|
Membrane repolarization during ventricular cardiac muscle cell action potential GO:0098915
The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
|
1 | O35219 (/ISO) |
|
Regulation of potassium ion transmembrane transport GO:1901379
Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | Q12809 (/IDA) |
|
Regulation of potassium ion transmembrane transport GO:1901379
Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | O35219 (/ISO) |
|
Negative regulation of potassium ion transmembrane transport GO:1901380
Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | Q12809 (/IDA) |
|
Negative regulation of potassium ion transmembrane transport GO:1901380
Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | O35219 (/ISO) |
|
Positive regulation of potassium ion transmembrane transport GO:1901381
Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | Q12809 (/IDA) |
|
Positive regulation of potassium ion transmembrane transport GO:1901381
Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | O35219 (/ISO) |
|
Negative regulation of potassium ion export GO:1902303
Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export.
|
1 | Q12809 (/IDA) |
|
Negative regulation of potassium ion export GO:1902303
Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export.
|
1 | O35219 (/ISO) |
There are 40 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | O95259 (/TAS) Q12809 (/TAS) Q8NCM2 (/TAS) Q96L42 (/TAS) Q9H252 (/TAS) Q9NS40 (/TAS) Q9UQ05 (/TAS) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
6 | A0A0B4LGW2 (/ISS) A1ZB14 (/ISS) O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) Q7JPB9 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | O08962 (/IDA) O54853 (/IDA) O95259 (/IDA) Q60603 (/IDA) Q63472 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | O35219 (/IDA) Q02280 (/IDA) Q12809 (/IDA) Q63472 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
3 | A0A0B4LGW2 (/NAS) A1ZB14 (/NAS) Q7JPB9 (/NAS) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
3 | O95259 (/TAS) Q02280 (/TAS) Q9UQ05 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | Q12809 (/IDA) Q63472 (/IDA) Q8NCM2 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | B3DJX4 (/ISS) E9QJ94 (/ISS) F6NT38 (/ISS) |
|
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | O18965 (/IMP) O95259 (/IMP) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
2 | O95259 (/IDA) Q12809 (/IDA) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
2 | O35219 (/ISO) Q60603 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | O35219 (/ISO) Q920E3 (/ISO) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q8NCM2 (/IDA) |
|
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
|
1 | Q920E3 (/ISO) |
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | O35219 (/IDA) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | Q63472 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O35219 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q12809 (/IMP) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O35219 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q60603 (/ISO) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
1 | Q12809 (/IMP) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
1 | Q02280 (/IPI) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O44164 (/IC) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q63472 (/IDA) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q63472 (/IDA) |
|
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
|
1 | Q63472 (/IDA) |
|
Microvillus membrane GO:0031528
The portion of the plasma membrane surrounding a microvillus.
|
1 | O44164 (/IDA) |
|
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
|
1 | O95259 (/IDA) |
|
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
|
1 | Q60603 (/ISO) |
|
Potassium channel complex GO:0034705
An ion channel complex through which potassium ions pass.
|
1 | Q63472 (/IDA) |
|
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
|
1 | Q63472 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q63472 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | O95259 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q60603 (/ISO) |
|
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q63472 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q63472 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q12809 (/IMP) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | O35219 (/ISO) |