The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Voltage-gated potassium channels. Chain C
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 4257: Protein BM-KVS-4, isoform b

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
3 H2KZE7 (/IDA) H2KZE8 (/IDA) Q7JPF0 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 H2KZE7 (/IPI) H2KZE8 (/IPI) Q7JPF0 (/IPI)
Inward rectifier potassium channel activity GO:0005242
Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
1 H2KZQ6 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 H2KZE7 (/IDA) H2KZE8 (/IDA) Q7JPF0 (/IDA)
Hyperosmotic response GO:0006972
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
3 H2KZE7 (/IMP) H2KZE8 (/IMP) Q7JPF0 (/IMP)
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
3 H2KZE7 (/IMP) H2KZE8 (/IMP) Q7JPF0 (/IMP)
Forward locomotion GO:0043056
Anterior movement of an organism, following the direction of the head of the animal.
3 H2KZE7 (/IMP) H2KZE8 (/IMP) Q7JPF0 (/IMP)
Regulation of chemotaxis GO:0050920
Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
3 H2KZE7 (/IMP) H2KZE8 (/IMP) Q7JPF0 (/IMP)
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
1 H2KZQ6 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
3 H2KZE7 (/IDA) H2KZE8 (/IDA) Q7JPF0 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 A5A8P9 (/IDA) Q95XV8 (/IDA)
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
1 H2KZQ6 (/IC)