An action potential that occurs in a neuron.

The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.

A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.

The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.

The propagation of an action potential along an axon, away from the soma.

An action potential that occurs in a neuron.

An action potential that occurs in a neuron.

Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.

Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.

The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.

An action potential that occurs in a cardiac muscle cell and is involved in its contraction.

An action potential that occurs in a cardiac muscle cell and is involved in its contraction.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.

A sodium channel in a cell membrane whose opening is governed by the membrane potential.

That part of the nuclear content other than the chromosomes or the nucleolus.

That part of the nuclear content other than the chromosomes or the nucleolus.

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.

Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.

Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.

Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.

The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.

An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.

An ion channel complex through which sodium ions pass.

The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.

Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.