The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 14688: Sodium/potassium-transporting ATPase alpha subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sodium/potassium-exchanging ATPase. [EC: 3.6.3.9]
ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
  • It is involved in generating the plasma membrane electrical potential.
  • Formerly EC 3.6.1.37.
46 A0A061HWK6 A0A0D9S121 A0A0S2Z3W6 A2VDL6 C0KXH0 D2WKD8 F7HPP6 H2N554 H9ZJM5 I6T816
(36 more...)
Hydrogen/potassium-exchanging ATPase. [EC: 3.6.3.10]
ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
  • Formerly EC 3.6.1.36.
14 A0A089WS23 P09626 P19156 P20648 P27112 P50996 P54707 P54708 Q64392 Q64436
(4 more...)