The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Dehydroquinate synthase-like - alpha domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6888: Alcohol dehydrogenase II AdhB

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alcohol dehydrogenase. [EC: 1.1.1.1]
(1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
  • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
  • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
540 A0A009GF88 A0A009GRS2 A0A009HMY2 A0A009KV27 A0A009NP49 A0A009R9J0 A0A009SKJ6 A0A010IY28 A0A010VLI8 A0A011KMU5
(530 more...)
1,3-propanediol dehydrogenase. [EC: 1.1.1.202]
Propane-1,3-diol + NAD(+) = 3-hydroxypropanal + NADH.
    198 A0A009GRS2 A0A009HMY2 A0A009KV27 A0A009R9J0 A0A009SKJ6 A0A023T4G6 A0A026UWS8 A0A027U618 A0A028ATC2 A0A028E2A1
    (188 more...)
    Methanol dehydrogenase. [EC: 1.1.1.244]
    Methanol + NAD(+) = formaldehyde + NADH.
      23 A0A0E1W2L9 A0A0H5KYV2 A0A0J1FLH9 A0A0N1QV72 A0A0U5C732 A0A1J7M5C3 A0A1L7H3E3 A3N9Q7 B1HX72 C9Y4J9
      (13 more...)
      Glycerol dehydrogenase. [EC: 1.1.1.6]
      Glycerol + NAD(+) = glycerone + NADH.
      • Also acts on 1,2-propanediol.
      5 A0A0F4W2I7 A0A0F4WHC2 B3LEU7 Q0G9E9 Q0G9F0
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