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CATH Superfamily 1.20.1090.10

Dehydroquinate synthase-like - alpha domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Dehydroquinate synthase-like - alpha domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6820: Probable hydroxyacid-oxoacid transhydrogenase, mit...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hydroxyacid-oxoacid transhydrogenase. [EC: 1.1.99.24]
(1) (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2- hydroxyglutarate. (2) 4-hydroxybutanoate + 2-oxoglutarate = succinic semialdehyde + (R)-2- hydroxyglutarate.
    		 16 A0A084FWN6 A6QP15 A8WTJ7 B4GHJ1 Q08B39 Q17EN4 Q28XT3 Q4QQW3 Q54GJ7 Q5RF11
    (6 more...)
    Alcohol dehydrogenase. [EC: 1.1.1.1]
    (1) An alcohol + NAD(+) = an aldehyde or ketone + NADH. (2) A secondary alcohol + NAD(+) = a ketone + NADH.
    • Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.
    • The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
    		 5 A0A0F4Z660 A0A0J6EXI4 C5PGY1 E9CWX9 J3KIR8
    Methanol dehydrogenase. [EC: 1.1.1.244]
    Methanol + NAD(+) = formaldehyde + NADH.
      		 3 A0A0P4U3W6 A2QVY9 B7Q4P9