The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
SV40 is made up of domains 1, 2 and 3.
This superfamily makes up domain 3, the only domain which plays no role in the multimerisation to form the hexameric form of large T antigen. Instead, domain 3 plays a role in p53 binding and binding polymerase machinery, evidenced by the protein's inability to bind p53 if certain mutations are introduced into domain 3.
Structures | |
---|---|
Domains: | 39 |
Domain clusters (>95% seq id): | 2 |
Domain clusters (>35% seq id): | 1 |
Unique PDBs: | 11 |
Alignments | |
Structural Clusters (5A): | 1 |
Structural Clusters (9A): | 1 |
FunFam Clusters: | 0 |
Function | |
Unique EC: | |
Unique GO: | 6 |
Taxonomy | |
Unique Species: | 201 |