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CATH Superfamily 1.20.1050.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15680: Glutathione S-transferase Mu 5

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutathione transferase. [EC: 2.5.1.18]
RX + glutathione = HX + R-S-glutathione.
  • A group of enzymes of broad specificity.
  • R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
  • Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange.
  • Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
 186 A0A067A415 A0A067A415 A0A077CUX1 A0A077CUX1 A0A077CXG0 A0A077CXG0 A0A077D014 A0A077D014 A0A077D0C3 A0A077D0C3
(176 more...)
Prostaglandin-D synthase. [EC: 5.3.99.2]
(5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
  • Brings about the opening of the epidioxy bridge.
 10 E0V9D7 E0V9D7 E0VL93 E0VL93 E0VL94 E0VL94 E0VL95 E0VL95 E9GD76 E9GD76
Glutathione peroxidase. [EC: 1.11.1.9]
2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
  • Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
 6 A0A0B4KFT5 A0A0B4KFT5 A4UZL5 A4UZL5 P41043 P41043
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