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CATH Superfamily 1.20.1050.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15572: Glutathione S-transferase 1, isoform B

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutathione transferase. [EC: 2.5.1.18]
RX + glutathione = HX + R-S-glutathione.
  • A group of enzymes of broad specificity.
  • R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
  • Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange.
  • Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
 128 A0A077CXE3 A0A077CXE3 A0A077D5Y7 A0A077D5Y7 A0A077D6E7 A0A077D6E7 A0A0A7KNK1 A0A0A7KNK1 A0A0A7KQB0 A0A0A7KQB0
(118 more...)
DDT-dehydrochlorinase. [EC: 4.5.1.1]
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2- bis(4-chlorophenyl)ethylene + chloride.
    		 20 A0A182IIQ8 A0A182IIQ8 A0A182XJ35 A0A182XJ35 P20432 P20432 P30104 P30104 P30106 P30106
    (10 more...)
    Glutathione peroxidase. [EC: 1.11.1.9]
    2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
    • Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 on phospholipids, can act as acceptor, but more slowly than H(2)O(2) (cf. EC 1.11.1.12).
    		 2 Q9VG92 Q9VG92
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