The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aromatic amino acid hydroxylase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 115: Tyrosine hydroxylase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Tyrosine 3-monooxygenase activity GO:0004511
Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Tyrosine 3-monooxygenase activity GO:0004511
Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
2 A0A060X6Z0 (/IDA) Q9PU40 (/IDA)
Tyrosine 3-monooxygenase activity GO:0004511
Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
1 B3DJW5 (/IMP)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Courtship behavior GO:0007619
The behavioral interactions between organisms for the purpose of attracting sexual partners.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Grooming behavior GO:0007625
The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Multi-organism behavior GO:0051705
Any process in which an organism has a behavioral effect on another organism of the same or different species.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Response to growth hormone GO:0060416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Courtship behavior GO:0007619
The behavioral interactions between organisms for the purpose of attracting sexual partners.
1 H0ZG94 (/IDA)
Grooming behavior GO:0007625
The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
1 H0ZG94 (/IDA)
Flight behavior GO:0007629
The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
1 H0ZG94 (/IDA)
Response to auditory stimulus GO:0010996
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
1 H0ZG94 (/IDA)
Spinal cord motor neuron differentiation GO:0021522
The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
1 B3DJW5 (/IMP)
Social behavior GO:0035176
Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
1 H0ZG94 (/IDA)
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
1 B3DJW5 (/IMP)
Dopamine biosynthetic process GO:0042416
The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
1 H0ZG94 (/TAS)
Norepinephrine biosynthetic process GO:0042421
The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
1 H0ZG94 (/TAS)
Multi-organism behavior GO:0051705
Any process in which an organism has a behavioral effect on another organism of the same or different species.
1 H0ZG94 (/IDA)
Response to growth hormone GO:0060416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
1 Q9PU40 (/IMP)
Vocalization behavior GO:0071625
The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
1 H0ZG94 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
28 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(18 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
27 A0A087RK40 (/ISS) A0A087VLC1 (/ISS) A0A091EE11 (/ISS) A0A091FQK1 (/ISS) A0A091HKB3 (/ISS) A0A091J4P8 (/ISS) A0A091M670 (/ISS) A0A091MU58 (/ISS) A0A091NUF6 (/ISS) A0A091PYZ9 (/ISS)
(17 more)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 H0ZG94 (/IDA) Q9PU40 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9PU40 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 H0ZG94 (/IMP)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
1 A0A060X6Z0 (/IDA)
Cell body fiber GO:0070852
A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.
1 A0A060X6Z0 (/IDA)