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CATH Superfamily 1.10.8.100

rRNA adenine dimethylase, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2512: Ribosomal RNA small subunit methyltransferase A

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase. [EC: 2.1.1.182]
4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)- dimethyladenine(1519) in 16S rRNA.
  • KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine(1518) and adenine(1519) in 16S rRNA.
  • Strains lacking the methylase are resistant to kasugamycin.
  • Formerly EC 2.1.1.48.
 1022 A0A011UM16 A0A011US98 A0A013VJQ5 A0A017HJG2 A0A021X0S1 A0A023D514 A0A023XFZ0 A0A024IPI6 A0A024LQA3 A0A031HLU3
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