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CATH Superfamily 1.10.8.10

Ubiquitin-associated (UBA) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
DNA helicase RuvA subunit, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4865: 16S rRNA methylase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
16S rRNA (guanine(1405)-N(7))-methyltransferase. [EC: 2.1.1.179]
S-adenosyl-L-methionine + guanine(1405) in 16S rRNA = S-adenosyl-L- homocysteine + N(7)-methylguanine(1405) in 16S rRNA.
  • The enzyme from the antibiotic-producing bacterium Micromonospora zionensis specifically methylates guanine(1405) at N(7) in 16S rRNA, thereby rendering the ribosome resistant to 4,6-disubstituted deoxystreptamine aminoglycosides, which include gentamicins and kanamycins.
 15 A0A059WPX8 A0A0B4ZQ92 A0A0E0X794 A0A0E3DSK3 A0A0F1EMM9 A0A0G3VJL1 A0A1C0BZS3 A0A1C0P1D3 A0A1D3A8I0 A0A1D3AN30
(5 more...)
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