The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"DNA helicase RuvA subunit, C-terminal domain
".
FunFam 15610: UBA domain-containing protein mud1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P52486 (/IPI) Q9M548 (/IPI) |
|
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
|
1 | Q10256 (/ISO) |
|
DNA (cytosine-5-)-methyltransferase activity GO:0003886
Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
|
1 | Q9LXE5 (/IMP) |
|
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
|
1 | P52486 (/ISS) |
|
DNA-methyltransferase activity GO:0009008
Catalysis of the transfer of a methyl group to a DNA molecule.
|
1 | Q9M548 (/IMP) |
|
Polyubiquitin binding GO:0031593
Interacting selectively and non-covalently with a polymer of ubiqutin.
|
1 | Q10256 (/IDA) |
|
Polyubiquitin binding GO:0031593
Interacting selectively and non-covalently with a polymer of ubiqutin.
|
1 | Q10187 (/TAS) |
|
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | P52486 (/IPI) |
|
Proteasome binding GO:0070628
Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
|
1 | P52486 (/IPI) |
There are 11 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA methylation GO:0006306
The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
|
2 | Q9LXE5 (/IMP) Q9M548 (/IMP) |
|
Gene silencing GO:0016458
Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
|
2 | Q9LXE5 (/IMP) Q9M548 (/IMP) |
|
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
|
2 | Q9LXE5 (/IGI) Q9M548 (/IGI) |
|
Histone H3-K9 methylation GO:0051567
The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.
|
2 | Q9LXE5 (/IGI) Q9M548 (/IGI) |
|
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
|
1 | P52486 (/ISS) |
|
Methylation-dependent chromatin silencing GO:0006346
Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
|
1 | Q9LXE5 (/IMP) |
|
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
|
1 | Q10256 (/ISO) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q10187 (/ISO) |
|
Regulation of exocytosis GO:0017157
Any process that modulates the frequency, rate or extent of exocytosis.
|
1 | Q10256 (/ISO) |
|
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | Q10256 (/TAS) |
|
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
|
1 | P52486 (/IDA) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10187 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q10187 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9M548 (/ISS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9M548 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q10187 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q10187 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q10256 (/ISO) |
