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CATH Superfamily 1.10.760.10

Cytochrome c-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cytochrome c-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5346: Nicotinate dehydrogenase subunit B

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Nicotinate dehydrogenase (cytochrome). [EC: 1.17.2.1]
Nicotinate + a ferricytochrome + H(2)O = 6-hydroxynicotinate + a ferrocytochrome + 2 H(+).
  • This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases, but differs from most other members of this family.
  • While most members contain an FAD cofactor, the large subunit of this enzyme contains three c-type cytochromes, enabling it to interact with the electron transfer chain, probably by delivering the electrons to a cytochrome oxidase.
 5 A0A0D0TBX6 A0A0S4IDT3 A0A1C3HDE7 Q88FX8 S0AGN7
Isoquinoline 1-oxidoreductase. [EC: 1.3.99.16]
Isoquinoline + acceptor + H(2)O = isoquinolin-1(2H)-one + reduced acceptor.
  • The enzyme from Pseudomonas diminuta is specific toward N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline.
  • Electron acceptors include 1,2-benzoquinone, cytochrome c, ferricyanide, iodonitrotetrazolium chloride (INT), nitroblue tetrazolium (NBT), Meldola blue and phenazine methosulfate.
 2 A0A0E3GXE4 A0A143GH48
Gluconate 2-dehydrogenase (acceptor). [EC: 1.1.99.3]
D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.
    		 1 W6V6A8
    Aldehyde dehydrogenase (quinone). [EC: 1.2.5.2]
    An aldehyde + a quinone + H(2)O = a carboxylate + a quinol.
    • Wide specificity; acts on straight-chain aldehydes up to C(10), aromatic aldehydes, glyoxylate and glyceraldehyde.
    • Formerly EC 1.2.99.3.
    		 1 W6V6A8
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