CATH Superfamily 1.10.720.40
The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 591: Emerin
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O08579 (/IPI) P50402 (/IPI) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | P50402 (/IDA) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | O08579 (/ISO) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | P50402 (/IDA) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | O08579 (/ISO) |
|
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
|
1 | P50402 (/IDA) |
|
Beta-tubulin binding GO:0048487
Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
|
1 | O08579 (/ISO) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Muscle contraction GO:0006936
A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
|
1 | P50402 (/TAS) |
|
Mitotic nuclear envelope disassembly GO:0007077
The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
|
1 | P50402 (/TAS) |
|
Mitotic nuclear envelope reassembly GO:0007084
The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
|
1 | P50402 (/TAS) |
|
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
1 | P50402 (/TAS) |
|
Nuclear envelope reassembly GO:0031468
The reformation of the nuclear envelope following its breakdown in the context of a normal process.
|
1 | Q63190 (/IEP) |
|
Negative regulation of catenin import into nucleus GO:0035414
Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.
|
1 | P50402 (/IMP) |
|
Negative regulation of catenin import into nucleus GO:0035414
Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.
|
1 | O08579 (/ISO) |
|
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
|
1 | O08579 (/IGI) |
|
Skeletal muscle cell differentiation GO:0035914
The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
|
1 | O08579 (/IMP) |
|
Positive regulation of protein export from nucleus GO:0046827
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
|
1 | P50402 (/IMP) |
|
Positive regulation of protein export from nucleus GO:0046827
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
|
1 | O08579 (/ISO) |
|
Negative regulation of fibroblast proliferation GO:0048147
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
|
1 | P50402 (/IMP) |
|
Negative regulation of fibroblast proliferation GO:0048147
Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
|
1 | O08579 (/ISO) |
|
Regulation of canonical Wnt signaling pathway GO:0060828
Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | P50402 (/IMP) |
|
Regulation of canonical Wnt signaling pathway GO:0060828
Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
|
1 | O08579 (/ISO) |
|
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | P50402 (/IMP) |
|
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | O08579 (/ISO) |
There are 23 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
3 | O08579 (/IDA) P50402 (/IDA) Q63190 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | P50402 (/IDA) Q5HY57 (/IDA) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
2 | P50402 (/IDA) Q5HY57 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | O08579 (/IDA) |
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | O08579 (/ISO) |
|
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
|
1 | P50402 (/TAS) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | P50402 (/IDA) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | O08579 (/ISO) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | P50402 (/NAS) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | O08579 (/TAS) |
|
Nuclear outer membrane GO:0005640
The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.
|
1 | P50402 (/IDA) |
|
Nuclear outer membrane GO:0005640
The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.
|
1 | O08579 (/ISO) |
|
Nuclear lamina GO:0005652
The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
|
1 | O08579 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | P50402 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | O08579 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P50402 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O08579 (/ISO) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | O08579 (/ISO) |
|
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
|
1 | Q63190 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P50402 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O08579 (/ISO) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q63190 (/IDA) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | O08579 (/ISO) |
