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CATH Superfamily 1.10.645.10

Cytochrome-c3 Hydrogenase, chain B

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cytochrome-c3 Hydrogenase, chain B
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4605: Nickel-dependent hydrogenase large subunit

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hydrogen dehydrogenase. [EC: 1.12.1.2]
H(2) + NAD(+) = H(+) + NADH.
    		 111 A0A011NF03 A0A011NYE4 A0A011Q8J4 A0A011QPE6 A0A068N133 A0A073CV30 A0A080LUE5 A0A080M086 A0A080M7X3 A0A084Y5D1
    (101 more...)
    Cytochrome-c3 hydrogenase. [EC: 1.12.2.1]
    H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.
    • Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases).
    • Methylene blue and other acceptors can also be reduced.
    		 1 Q59114