View in Gene3D

CATH Superfamily 1.10.620.20

Ribonucleotide Reductase, subunit A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribonucleotide Reductase, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3327: Acyl-[acyl-carrier-protein] desaturase 2, chloropl...

There are 5 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Stearoyl-[acyl-carrier-protein] 9-desaturase. [EC: 1.14.19.2]
Stearoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O(2) + 2 H(+) = oleoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H(2)O.
  • The enzyme is found in the lumen of plastids, where de novo biosynthesis of fatty acids occurs, and acts on freshly synthesized saturated fatty acids that are still linked to acyl-carrier protein.
  • The enzyme determines the position of the double bond by its distance from the carboxylic acid end of the fatty acid.
  • It also acts on palmitoyl-[acyl-carrier-protein].
  • Formerly EC 1.14.99.6.
 73 A0A076NS96 A0A077XQN4 A0A078D558 A0A090VQH8 A0A090W1Q2 A0A090WVT1 A0A098LPQ3 A0A0B2QGC4 A0A0D2JH23 A0A0D2KZ35
(63 more...)
Acyl-[acyl-carrier-protein] 4-desaturase. [EC: 1.14.19.11]
Palmitoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O(2) = (4Z)-hexadec-4-enoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H(2)O.
  • The enzymes from the plants Coriandrum sativum (coriander) and Hedera helix are involved in biosynthesis of petroselinate ((6Z)-octadec-6- enoate), which is formed by elongation of (4Z)-hexadec-4-enoate.
  • The ivy enzyme can also act on oleoyl-[acyl-carrier protein] and palmitoleoyl-[acyl-carrier protein], generating the corresponding 4,9-diene.
 10 E3PZR9 E3PZS0 E3PZS1 E3PZS2 E3PZS3 H9NA46 H9NA55 M1F1Q4 P32063 Q3L0U4
Stearoyl-CoA 9-desaturase. [EC: 1.14.19.1]
Stearoyl-CoA + 2 ferrocytochrome b5 + O(2) + 2 H(+) = oleoyl-CoA + 2 ferricytochrome b5 + 2 H(2)O.
  • The liver enzyme is an enzyme system involving cytochrome b5 and EC 1.6.2.2.
  • The ferricytochrome b5 produced is reduced by NADH and EC 1.6.2.2.
  • Formerly EC 1.14.99.5.
 1 A0A172ZPI5
Transferred entry: 1.14.19.2. [EC: 1.14.99.6]
    		1 Q43197
    Acyl-[acyl-carrier-protein] 6-desaturase. [EC: 1.14.19.26]
    Palmitoyl-[acyl-carrier protein] + 2 reduced ferredoxin [iron-sulfur] cluster + O(2) + 2 H(+) = (6Z)-hexadec-6-enoyl-[acyl-carrier protein] + 2 oxidized ferredoxin [iron-sulfur] cluster + 2 H(2)O.
    • The enzyme, characterized from the endosperm of the plant Thunbergia alata (black-eyed Susan vine), introduces a cis double bond at carbon 6 of several saturated acyl-[acyl-carrier protein]s.
    • It is most active with palmitoyl-[acyl-carrier protein] (16:0), but can also act on myristoyl-[acyl-carrier protein] (14:0) and stearoyl-[acyl-carrier protein] (18:0).
    • The position of the double bond is determined by its distance from the carboxyl end of the fatty acid.
    		 1 Q41510
    CATH-Gene3D is a Global Biodata Core Resource Learn more...