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CATH Superfamily 1.10.569.10

Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldehyde Ferredoxin Oxidoreductase Protein, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 401: Tungsten-containing aldehyde ferredoxin oxidoreduc...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aldehyde ferredoxin oxidoreductase. [EC: 1.2.7.5]
An aldehyde + H(2)O + 2 oxidized ferredoxin = a carboxylate + 2 H(+) + 2 reduced ferredoxin.
  • This is an oxygen-sensitive enzyme.
  • Catalyzes the oxidation of aldehydes (including crotonaldehyde, acetaldehyde, formaldehyde and glyceraldehyde) to their corresponding acids.
  • However, it does not oxidize glyceraldehyde 3-phosphate (see EC 1.2.7.6).
  • Can use ferredoxin or methyl viologen but not NAD(P)(+) as electron acceptor.
 16 A0A0S1XCJ7 A0A0U2Z6J8 A0A0U3RVU6 A0A101F1T5 A0A160VTE7 C5A1Z6 C6A1P7 C6A370 D3TB67 G7VAH1
(6 more...)
Glyceraldehyde-3-phosphate dehydrogenase (ferredoxin). [EC: 1.2.7.6]
D-glyceraldehyde-3-phosphate + H(2)O + 2 oxidized ferredoxin = 3-phospho- D-glycerate + 2 H(+) + 2 reduced ferredoxin.
  • Thought to function in place of glyceraldehyde-3-phosphate dehydrogenase and possibly phosphoglycerate kinase in the novel Embden-Meyerhof-type glycolytic pathway found in Pyrococcus furiosus.
  • Specific for glyceraldehyde-3-phosphate.
 2 I6UZU7 Q8U3K2