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CATH Superfamily 1.10.530.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12391: Membrane-bound lytic murein transglycosylase D

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Peptidoglycan lytic exotransglycosylase. [EC: 4.2.2.n1]
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.
    		 189 A0A023YSC4 A0A024KTB2 A0A025BWN6 A0A026RN36 A0A026URH3 A0A028AK91 A0A028E3X7 A0A029IDE3 A0A029J262 A0A029L3E1
    (179 more...)
    Hyaluronate lyase. [EC: 4.2.2.1]
    Cleaves hyaluronate chains at a beta-D-GlcNAc-(1->4)-beta-D-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4- enuronosyl)-N-acetyl-D-glucosamine.
    • The enzyme catalyzes the degradation of hyaluronan by a beta- elimination reaction.
    • Also acts on chondroitin.
    • The product is more systematically known as 3-(4-deoxy-alpha-L-threo- hex-4-enopyranosyluronic acid)-2-acetamido-2-deoxy-D-glucose.
    • Formerly EC 4.2.99.1.
    		 2 S0ABF5 S4YFL4