The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 79392: Tribbles homolog 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 20 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 Q7TNL3 (/IPI) Q8K4K2 (/IPI) Q8N2I9 (/IPI) Q96RU7 (/IPI) Q96RU8 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
3 Q8K4K2 (/ISS) Q96RU7 (/ISS) Q9WTQ6 (/ISS)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
3 Q8K4K2 (/IDA) Q8K4K3 (/IDA) Q8K4K4 (/IDA)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
3 Q92519 (/ISS) Q96RU7 (/ISS) Q96RU8 (/ISS)
Ubiquitin-protein transferase regulator activity GO:0055106
Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
3 Q8K4K2 (/IDA) Q8K4K3 (/IDA) Q8K4K4 (/IDA)
Ubiquitin-protein transferase regulator activity GO:0055106
Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
3 Q92519 (/ISS) Q96RU7 (/ISS) Q96RU8 (/ISS)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
2 Q96RU7 (/ISS) Q9WTQ6 (/ISS)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
2 Q8K4K3 (/IDA) Q8K4K4 (/IDA)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
2 Q8K4K4 (/IPI) Q96RU8 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
2 Q8K4K2 (/IPI) Q96RU7 (/IPI)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 Q8K4K2 (/IDA)
Protein kinase inhibitor activity GO:0004860
Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein.
1 Q96RU8 (/IMP)
Protein kinase inhibitor activity GO:0004860
Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein.
1 Q8K4K4 (/ISO)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
1 Q8K4K4 (/ISO)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
1 Q92519 (/ISS)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q8K4K2 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 Q8K4K2 (/ISO)
Mitogen-activated protein kinase kinase binding GO:0031434
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase.
1 Q96RU8 (/IDA)
Mitogen-activated protein kinase kinase binding GO:0031434
Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase.
1 Q8K4K4 (/ISO)
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
1 Q8K4K2 (/IPI)

There are 72 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of MAP kinase activity GO:0043405
Any process that modulates the frequency, rate or extent of MAP kinase activity.
8 Q28283 (/ISS) Q5GLH2 (/ISS) Q5R669 (/ISS) Q8K4K2 (/ISS) Q8K4K3 (/ISS) Q8K4K4 (/ISS) Q92519 (/ISS) Q9WTQ6 (/ISS)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
3 Q0VCE3 (/ISS) Q8K4K2 (/ISS) Q9WTQ6 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
3 Q0VCE3 (/ISS) Q8K4K2 (/ISS) Q9WTQ6 (/ISS)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
3 Q0VCE3 (/ISS) Q8K4K2 (/ISS) Q9WTQ6 (/ISS)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
2 Q8K4K2 (/IDA) Q96RU7 (/IDA)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
2 Q8K4K2 (/ISO) Q8K4K4 (/ISO)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 Q8K4K3 (/IDA) Q8K4K4 (/IDA)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 Q92519 (/ISS) Q96RU8 (/ISS)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
2 Q8K4K4 (/IMP) Q96RU8 (/IMP)
Regulation of MAP kinase activity GO:0043405
Any process that modulates the frequency, rate or extent of MAP kinase activity.
2 Q96RU7 (/IDA) Q96RU8 (/IDA)
Regulation of MAP kinase activity GO:0043405
Any process that modulates the frequency, rate or extent of MAP kinase activity.
2 Q8K4K2 (/ISO) Q8K4K4 (/ISO)
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
2 Q8K4K2 (/IMP) Q8K4K3 (/IMP)
Negative regulation of fat cell differentiation GO:0045599
Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
2 Q92519 (/ISS) Q96RU7 (/ISS)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
2 Q8K4K3 (/IC) Q8K4K4 (/IC)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q96RU7 (/IDA)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q8K4K2 (/ISO)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 E7FD70 (/IMP)
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
1 F1QCV8 (/IMP)
Respiratory system process GO:0003016
A system process carried out by the organs and tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.
1 Q7TNL3 (/IMP)
Glycogen metabolic process GO:0005977
The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
1 Q7TNL3 (/IMP)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
1 Q96RU8 (/IMP)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
1 Q9WTQ6 (/ISS)
Negative regulation of protein kinase activity GO:0006469
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
1 Q92519 (/NAS)
JNK cascade GO:0007254
An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
1 Q96RU8 (/IMP)
JNK cascade GO:0007254
An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
1 Q8K4K4 (/ISO)
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
1 F1QCV8 (/IMP)
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 Q7TNL3 (/IMP)
Regulation of glucose transport GO:0010827
Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8K4K2 (/IDA)
Regulation of glucose transport GO:0010827
Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q96RU7 (/ISS)
Programmed cell death GO:0012501
A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
1 Q9WTQ6 (/NAS)
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
1 Q96RU8 (/IMP)
Negative regulation of smooth muscle cell migration GO:0014912
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
1 Q8K4K4 (/ISO)
Regulation of lipid metabolic process GO:0019216
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
1 Q96RU7 (/TAS)
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
1 Q7TNL3 (/IMP)
Negative regulation of lipopolysaccharide-mediated signaling pathway GO:0031665
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
1 Q96RU8 (/IMP)
Negative regulation of lipopolysaccharide-mediated signaling pathway GO:0031665
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
1 Q8K4K4 (/ISO)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 Q8K4K2 (/IDA)
Positive regulation of protein binding GO:0032092
Any process that activates or increases the frequency, rate or extent of protein binding.
1 Q96RU7 (/ISS)
Positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436
Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
1 Q8K4K2 (/TAS)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q8K4K4 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q96RU8 (/ISS)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 Q8K4K2 (/IDA)
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
1 Q96RU7 (/ISS)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q96RU7 (/IDA)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q8K4K2 (/ISO)
Multicellular organism growth GO:0035264
The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
1 Q7TNL3 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q7TNL3 (/IMP)
Regulation of MAPK cascade GO:0043408
Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
1 Q7TNL3 (/IMP)
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 Q8K4K3 (/IC)
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 Q8K4K4 (/IDA)
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 Q96RU8 (/IMP)
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 Q8K4K4 (/ISO)
Negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 Q96RU8 (/ISS)
Negative regulation of interleukin-10 biosynthetic process GO:0045081
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10.
1 Q92519 (/IMP)
Negative regulation of interleukin-10 biosynthetic process GO:0045081
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10.
1 Q8K4K3 (/ISO)
Positive regulation of eosinophil differentiation GO:0045645
Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.
1 Q8K4K4 (/IMP)
Positive regulation of macrophage differentiation GO:0045651
Any process that activates or increases the frequency, rate or extent of macrophage differentiation.
1 Q8K4K4 (/IMP)
Negative regulation of neutrophil differentiation GO:0045659
Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.
1 Q8K4K4 (/IMP)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
1 Q8K4K2 (/IMP)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
1 Q96RU7 (/ISS)
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
1 Q8K4K2 (/IC)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q96RU7 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q8K4K2 (/ISO)
Lung alveolus development GO:0048286
The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
1 Q7TNL3 (/IMP)
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
1 Q96RU8 (/IMP)
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
1 Q8K4K4 (/ISO)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
1 Q8K4K2 (/IDA)
Positive regulation of ubiquitin-protein transferase activity GO:0051443
Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
1 Q96RU7 (/ISS)
Lung morphogenesis GO:0060425
The process in which the anatomical structures of the lung are generated and organized.
1 Q7TNL3 (/IMP)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q96RU7 (/IDA)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q8K4K2 (/ISO)
Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q96RU7 (/TAS)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q5GLH2 (/ISS) Q5R669 (/ISS) Q8K4K3 (/ISS) Q92519 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 J3KR25 (/IDA) Q8K4K2 (/IDA) Q96RU8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8K4K2 (/ISO) Q8K4K4 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q96RU7 (/ISS) Q9WTQ6 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q28283 (/IDA) Q96RU8 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8N2I9 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q7TNL3 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 J3KR25 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q8K4K2 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8K4K4 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8N2I9 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q7TNL3 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q96RU7 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q96RU7 (/TAS)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 J3KR25 (/IDA)
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
1 Q8K4K2 (/ISO)