The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Cyclin-like
".
FunFam 9654: G2/mitotic-specific cyclin CYB1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538
Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
|
6 | P24868 (/IMP) P24869 (/IMP) P24870 (/IMP) P24871 (/IMP) Q5A0A9 (/IMP) Q5ALY0 (/IMP) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P10815 (/IPI) P24868 (/IPI) P24869 (/IPI) P24870 (/IPI) P36630 (/IPI) |
Cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538
Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
|
2 | P24869 (/IDA) Q5ALY0 (/IDA) |
Cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538
Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
|
2 | Q5A0A9 (/ISS) Q5ALY0 (/ISS) |
Cyclin-dependent protein serine/threonine kinase activator activity GO:0061575
Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.
|
2 | P10815 (/IGI) P36630 (/IGI) |
Cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538
Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
|
1 | P24865 (/NAS) |
Cyclin-dependent protein serine/threonine kinase activator activity GO:0061575
Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.
|
1 | P36630 (/IDA) |
There are 40 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079
Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
|
6 | P24868 (/IMP) P24869 (/IMP) P24870 (/IMP) P24871 (/IMP) Q5A0A9 (/IMP) Q5ALY0 (/IMP) |
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
4 | P24868 (/IMP) P24869 (/IMP) P24870 (/IMP) P24871 (/IMP) |
Positive regulation of spindle pole body separation GO:0010696
Any process that increases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
|
4 | P24868 (/IGI) P24869 (/IGI) P24870 (/IGI) P24871 (/IGI) |
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
3 | P24868 (/IGI) P24870 (/IGI) P24871 (/IGI) |
Regulation of mitotic cell cycle GO:0007346
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
|
2 | Q5A0A9 (/IMP) Q5ALY0 (/IMP) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
2 | Q5A0A9 (/IMP) Q5ALY0 (/IMP) |
Regulation of mitotic spindle assembly GO:1901673
Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
|
2 | P24870 (/IGI) P24871 (/IGI) |
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
1 | P24869 (/IEP) |
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
1 | P24868 (/ISS) |
Traversing start control point of mitotic cell cycle GO:0007089
A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
|
1 | P36630 (/IGI) |
Meiosis II GO:0007135
The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
|
1 | P24870 (/IDA) |
Meiosis II GO:0007135
The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
|
1 | P24870 (/IEP) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | P10815 (/NAS) |
Regulation of mitotic cell cycle GO:0007346
Any process that modulates the rate or extent of progress through the mitotic cell cycle.
|
1 | Q5ALY0 (/IDA) |
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.
|
1 | P10815 (/IMP) |
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any process that increases the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.
|
1 | P10815 (/TAS) |
Mitotic spindle organization in nucleus GO:0030472
A process resulting in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle in the nucleus. The process occurs during a mitotic cell cycle and takes place at the cellular level.
|
1 | P24868 (/IGI) |
Mitotic spindle organization in nucleus GO:0030472
A process resulting in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle in the nucleus. The process occurs during a mitotic cell cycle and takes place at the cellular level.
|
1 | P24868 (/IMP) |
Negative regulation of conjugation with cellular fusion GO:0031138
Any process that decreases the rate or frequency of conjugation with cellular fusion.
|
1 | P36630 (/IMP) |
Positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031659
Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
|
1 | P36630 (/IMP) |
Regulation of mitotic spindle elongation GO:0032888
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.
|
1 | P24869 (/IMP) |
Negative regulation of protein dephosphorylation GO:0035308
Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.
|
1 | P24869 (/IDA) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q5ALY0 (/IMP) |
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
|
1 | P36630 (/IGI) |
Positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737
Any process that activates or increases the frequency, rate or extent of CDK activity.
|
1 | P24869 (/IDA) |
Positive regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045737
Any process that activates or increases the frequency, rate or extent of CDK activity.
|
1 | P24869 (/IMP) |
Negative regulation of meiotic cell cycle GO:0051447
Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
|
1 | P10815 (/IMP) |
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
|
1 | P24868 (/IDA) |
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
|
1 | P24868 (/IEP) |
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
|
1 | P24868 (/IGI) |
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
|
1 | P24868 (/IMP) |
Signal transduction involved in G1 cell size control checkpoint GO:0072450
A signal transduction process that contributes to a mitotic cell cycle G1/S transition size control checkpoint.
|
1 | P36630 (/IGI) |
Negative regulation of ascospore formation GO:0075297
Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.
|
1 | P10815 (/IMP) |
Correction of merotelic kinetochore attachment, mitotic GO:0098783
The cell cycle process that corrects the anomalous association of a single chromatid kinetochore with mitotic spindle microtubules emanating from both spindle poles (otherwise known as merotelic attachment to the spindle).
|
1 | P10815 (/IGI) |
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the mitotic cell cycle.
|
1 | P36630 (/IGI) |
Positive regulation of G1/S transition of mitotic cell cycle GO:1900087
Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the mitotic cell cycle.
|
1 | P36630 (/IMP) |
Positive regulation of protein localization to nucleus GO:1900182
Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
|
1 | P10815 (/IMP) |
Positive regulation of double-strand break repair via homologous recombination GO:1905168
Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.
|
1 | P10815 (/IGI) |
Positive regulation of double-strand break repair via homologous recombination GO:1905168
Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.
|
1 | P10815 (/IMP) |
Regulation of G1/S transition of mitotic cell cycle GO:2000045
Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
|
1 | P24865 (/IMP) |
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
6 | P10815 (/IDA) P24868 (/IDA) P24869 (/IDA) P24870 (/IDA) P24871 (/IDA) P36630 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P10815 (/IDA) P24868 (/IDA) P24869 (/IDA) P24870 (/IDA) P24871 (/IDA) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | P10815 (/IDA) P36630 (/IDA) |
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
2 | P10815 (/IDA) P36630 (/IDA) |
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
|
1 | P36630 (/EXP) |
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
|
1 | P24868 (/IDA) |
Cyclin-dependent protein kinase holoenzyme complex GO:0000307
Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
|
1 | P24868 (/IMP) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P10815 (/EXP) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | P10815 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P24869 (/IMP) |
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
|
1 | P24869 (/IDA) |
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
|
1 | P24869 (/IDA) |
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
|
1 | P24869 (/IDA) |
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
|
1 | P10815 (/EXP) |
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
|
1 | P10815 (/IDA) |
Mitotic spindle pole body GO:0044732
The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
|
1 | P10815 (/EXP) |
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | P10815 (/EXP) |
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | P10815 (/IDA) |
Meiotic spindle GO:0072687
A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.
|
1 | P10815 (/IDA) |
Mitotic spindle midzone GO:1990023
The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
|
1 | P10815 (/IDA) |
Mitotic spindle midzone GO:1990023
The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
|
1 | P10815 (/IMP) |