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CATH Superfamily 1.10.45.10

Vanillyl-alcohol Oxidase; Chain A, domain 4

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vanillyl-alcohol Oxidase; Chain A, domain 4
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3344: Glycolate oxidase, subunit GlcD

There are 9 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
(S)-2-hydroxy-acid oxidase. [EC: 1.1.3.15]
(S)-2-hydroxy acid + O(2) = 2-oxo acid + H(2)O(2).
  • Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids; the B form preferentially oxidizes long-chain and aromatic hydroxy acids.
  • The rat isoenzyme B also acts as EC 1.4.3.2.
  • Formerly EC 1.1.3.1.
 185 A0A024BWL2 A0A024KNK0 A0A025CTB2 A0A027TZP6 A0A028E5P8 A0A061CL74 A0A061CNB8 A0A064TE95 A0A066STV3 A0A070DLD7
(175 more...)
D-lactate dehydrogenase (cytochrome). [EC: 1.1.2.4]
(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+).
    		 168 A0A031GJS0 A0A063BCK3 A0A063BPQ5 A0A070UNM0 A0A074IGB4 A0A077S490 A0A078BKG8 A0A085EWE7 A0A087CEH4 A0A087CVG9
    (158 more...)
    Glycolate dehydrogenase. [EC: 1.1.99.14]
    Glycolate + acceptor = glyoxylate + reduced acceptor.
    • Also acts on (R)-lactate.
    • 2,6-dichloroindophenol and phenazine methosulfate can act as acceptors.
    		 142 A0A023Z2B4 A0A023Z2L0 A0A025CUC1 A0A026VBL3 A0A027U0T6 A0A027ZEV7 A0A028E6J8 A0A029PDD1 A0A060A1J2 A0A060A1U4
    (132 more...)
    4-methylphenol dehydrogenase (hydroxylating). [EC: 1.17.99.1]
    4-methylphenol + 2 acceptor + H(2)O = 4-hydroxybenzaldehyde + 2 reduced acceptor.
    • Phenazine methosulfate can act as acceptor.
    • A quinone methide is probably formed as intermediate.
    • The first hydroxylation forms 4-hydroxybenzyl alcohol; a second hydroxylation converts this into 4-hydroxybenzaldehyde.
    		 36 A0A077FEB1 A0A0C3N0G6 A0A0D5LY54 A0A0D5VFL6 A0A0E2YZA1 A0A0F7KYN6 A0A0F7KZ72 A0A0K1J883 A0A0S4P446 A0A117KJ62
    (26 more...)
    Vanillyl-alcohol oxidase. [EC: 1.1.3.38]
    Vanillyl alcohol + O(2) = vanillin + H(2)O(2).
    • Converts a wide range of 4-hydroxybenzyl alcohols and 4-hydroxybenzylamines into the corresponding aldehydes.
    • The allyl group of 4-allylphenols is also converted into the -CH=CH-CH(2)OH group.
    		 12 A0A084FXN6 A0A084GCB4 A0A084GHW2 A0A0F4YIA3 A0A0F4YJ32 A0A0P4U405 B8M1T5 B8MGJ2 I4EYC0 P56216
    (2 more...)
    D-lactate dehydrogenase. [EC: 1.1.1.28]
    (R)-lactate + NAD(+) = pyruvate + NADH.
      		 7 A0A061YSH7 A0A0B0H7X2 M5CJ01 M5CTC2 Q3BXG8 W4S9M5 W4SL39
      UDP-N-acetylmuramate dehydrogenase. [EC: 1.3.1.98]
      UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
      • NADH can to a lesser extent replace NADPH.
      • Formerly EC 1.1.1.158.
      		 2 A0A0C1HEY4 A0A0P4U405
      L-2-hydroxyglutarate dehydrogenase. [EC: 1.1.99.2]
      (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
        		 1 W8X0W9
        Alkylglycerone-phosphate synthase. [EC: 2.5.1.26]
        1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
        • The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.
        		 1 A0A0G3H0K7