The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5462: Fumarate hydratase class II

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Fumarate hydratase. [EC: 4.2.1.2]
(S)-malate = fumarate + H(2)O.
    131 A0A031J2L9 A0A034TIA1 A0A059L1P8 A0A060HAI1 A0A061Q7P7 A0A069PYL7 A0A075PD89 A0A077LHH9 A0A081Y607 A0A085RIY8
    (121 more...)
    Aspartate ammonia-lyase. [EC: 4.3.1.1]
    L-aspartate = fumarate + NH(3).
      2 A0A1L2EMM2 A0A1N7UA96
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