The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5458: Fumarate hydratase class II

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Fumarate hydratase. [EC: 4.2.1.2]
(S)-malate = fumarate + H(2)O.
    482 A0A022MS84 A0A024K4F7 A0A024M9K1 A0A024QT61 A0A045IXZ8 A0A049DW23 A0A051TQE2 A0A064CQ37 A0A066YEU3 A0A069JK22
    (472 more...)
    Aspartate ammonia-lyase. [EC: 4.3.1.1]
    L-aspartate = fumarate + NH(3).
      5 A0A1L7CB20 A0A1L7CF17 A0A1L7CZ62 A0A1L7DB86 W4I4A9
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