The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (C-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5393: Bifunctional argininosuccinate lyase/N-acetylgluta...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Argininosuccinate lyase. [EC: 4.3.2.1]
2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.
    2136 A0A011AT67 A0A014PZL8 A0A017I4H7 A0A022PGB5 A0A023E5E7 A0A023RDD0 A0A023V626 A0A023Z622 A0A024KLQ8 A0A025C259
    (2126 more...)
    Amino-acid N-acetyltransferase. [EC: 2.3.1.1]
    Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
    • Also acts with L-aspartate and, more slowly, with some other amino acids.
    3 A0A0B8PZW1 Q9K3D6 Q9K3D7
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